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(S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone

CAS 58879-34-8C12H14O5SChemical Synthesis

(S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone (CAS: 58879-34-8), with the molecular formula C12H14O5S and a molecular weight of 270.30 g/mol, is a chiral building block utilized in organic synthesis. It serves as a valuable intermediate in the construction of complex molecules, particularly where stereochemical control is essential. This lactone derivative is employed in various chemical synthesis pathways, contributing to advancements in asymmetric synthesis.

IUPAC
(S)-(+)-γ-Tosyloxymethyl-γ-butyrolactone
Synonyms
(S)-(+)-γ-Tosyloxymethyl-γ-butyrolactone
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(S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone (C12H14O5S) — chemical structure, CAS 58879-34-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksLactonesOrganic Building Blocks
01 /Applications

Chiral Building Block

This compound acts as a stereodefined precursor in the synthesis of chiral molecules. Its specific configuration is leveraged to introduce or maintain desired stereochemistry in target compounds.

Intermediate in Organic Synthesis

It serves as a versatile intermediate, enabling the formation of new carbon-carbon or carbon-heteroatom bonds in multi-step synthetic sequences.

Asymmetric Synthesis

The inherent chirality of this furanone derivative makes it suitable for applications in asymmetric synthesis, facilitating the creation of enantiomerically enriched products.

Lactone Chemistry

As a functionalized lactone, it participates in ring-opening and modification reactions characteristic of this important class of organic compounds.

02 /Properties
Molecular weight270.30
Empirical formulaC12H14O5S
Assay98%
Optical activity[α]20/D +46°, c = 1 in chloroform
Melting point86-88 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
58879-34-8
MDL number
MFCD00082548
PubChem substance
24862440
Beilstein registry
4701928
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone used for?

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This compound is primarily used as a chiral building block and intermediate in organic synthesis, particularly in asymmetric synthesis and lactone chemistry.

What is the CAS number and molecular formula?

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The CAS number is 58879-34-8 and the molecular formula is C12H14O5S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product at a minimum purity of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should (S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone be handled?

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Handle with appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. It is classified as a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).

Is this chemical exported or shipped internationally?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.

How can I request a sample or quote?

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Please contact our sales team via the website or by telephone to request a sample or a quotation for this product.

Need (S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone in a specific grade or volume?