(S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone
(S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone (CAS: 58879-34-8), with the molecular formula C12H14O5S and a molecular weight of 270.30 g/mol, is a chiral building block utilized in organic synthesis. It serves as a valuable intermediate in the construction of complex molecules, particularly where stereochemical control is essential. This lactone derivative is employed in various chemical synthesis pathways, contributing to advancements in asymmetric synthesis.
- IUPAC
- (S)-(+)-γ-Tosyloxymethyl-γ-butyrolactone
- Synonyms
- (S)-(+)-γ-Tosyloxymethyl-γ-butyrolactone

Chiral Building Block
This compound acts as a stereodefined precursor in the synthesis of chiral molecules. Its specific configuration is leveraged to introduce or maintain desired stereochemistry in target compounds.
Intermediate in Organic Synthesis
It serves as a versatile intermediate, enabling the formation of new carbon-carbon or carbon-heteroatom bonds in multi-step synthetic sequences.
Asymmetric Synthesis
The inherent chirality of this furanone derivative makes it suitable for applications in asymmetric synthesis, facilitating the creation of enantiomerically enriched products.
Lactone Chemistry
As a functionalized lactone, it participates in ring-opening and modification reactions characteristic of this important class of organic compounds.
| Molecular weight | 270.30 |
|---|---|
| Empirical formula | C12H14O5S |
| Assay | 98% |
| Optical activity | [α]20/D +46°, c = 1 in chloroform |
| Melting point | 86-88 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone used for?
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This compound is primarily used as a chiral building block and intermediate in organic synthesis, particularly in asymmetric synthesis and lactone chemistry.
What is the CAS number and molecular formula?
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The CAS number is 58879-34-8 and the molecular formula is C12H14O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should (S)-(+)-Dihydro-5-(p-tolylsulfonyloxymethyl)-2(3H)-furanone be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. It is classified as a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
Is this chemical exported or shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.
How can I request a sample or quote?
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Please contact our sales team via the website or by telephone to request a sample or a quotation for this product.
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