(S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′−bi-2-naphthol
(S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol (CAS: 65355-00-2) is a chiral organic compound with the molecular formula C20H22O2 and a molecular weight of 294.39 g/mol. It serves as a valuable building block and ligand in asymmetric synthesis and catalysis. Its specific stereochemistry makes it highly sought after for the development of enantioselective reactions, particularly in pharmaceutical and fine chemical research.
- Synonyms
- 6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol
Chiral Ligand in Asymmetric Catalysis
This compound functions as a chiral ligand in various transition metal-catalyzed asymmetric reactions. Its rigid bi-naphthol backbone allows for effective control over stereoselectivity, enabling the synthesis of chiral molecules with high enantiomeric purity.
Building Block for Chiral Auxiliaries
It can be employed as a precursor for the synthesis of more complex chiral auxiliaries and catalysts. These derived compounds find applications in stereoselective transformations and the resolution of racemic mixtures.
Research in Enantioselective Synthesis
Researchers utilise (S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol in the development of novel synthetic methodologies. Its well-defined chiral environment is instrumental in designing new routes for accessing enantiomerically pure compounds.
| Molecular weight | 294.39 |
|---|---|
| Empirical formula | C20H22O2 |
| Assay | 97% |
| Optical activity | [α]20/D −75°, c = 1 in THF |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 165-169 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol used for?
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(S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol is primarily used as a chiral ligand in asymmetric synthesis and catalysis, and as a building block for chiral auxiliaries in chemical research and development.
What is the CAS number and chemical formula?
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The CAS number is 65355-00-2 and the empirical formula is C20H22O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol with an assay of 97% and an optical purity of ee: 99%. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should this chemical be handled safely?
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This compound is a Warning irritant to skin, eyes, and respiratory tract (H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area.
How is this product packed and exported?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging for safe handling, transport, and export of chemicals according to international regulations.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(−)-5,5′,6,6′,7,7′,8,8′-Octahydro-1,1′-bi-2-naphthol, please contact our sales department through the website or by phone.
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