(R)-5-Acetoxy-1-chlorohexane
(R)-5-Acetoxy-1-chlorohexane (CAS 154885-34-4) is a chiral building block with the molecular formula CH3CO2CH(CH3)[(CH2)4Cl] and a molecular weight of 178.66 g/mol. This organic compound serves as a valuable intermediate in asymmetric synthesis and general chemical manufacturing. Its structure, featuring both a protected alcohol and a halogen, allows for diverse downstream reactions. TSS supplies this chemical for research and development purposes.
![(R)-5-Acetoxy-1-chlorohexane (CH3CO2CH(CH3)[(CH2)4Cl]) — chemical structure, CAS 154885-34-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F154885-34-4.png&w=3840&q=75)
Chiral Building Block in Asymmetric Synthesis
(R)-5-Acetoxy-1-chlorohexane is utilised as a chiral synthon in the construction of enantiomerically pure complex molecules. Its defined stereochemistry is crucial for introducing chirality into target compounds.
Intermediate in Organic Synthesis
The presence of both an acetoxy group and a terminal chlorine atom makes this compound a versatile intermediate for various organic transformations. It can undergo nucleophilic substitution or modifications of the ester functionality.
Protected Alcohol Precursor
The acetoxy group acts as a protecting group for a secondary alcohol. This allows selective reactions to occur at the chloroalkyl chain before deprotection to reveal the alcohol.
| Molecular weight | 178.66 |
|---|---|
| Linear formula | CH3CO2CH(CH3)[(CH2)4Cl] |
| Assay | 99% |
| Boiling point | 220 °C(lit.) |
| Density | 1.02 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4365(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 100 °C / 212 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-40 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-5-Acetoxy-1-chlorohexane used for?
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(R)-5-Acetoxy-1-chlorohexane is primarily used as a chiral building block in asymmetric synthesis and as a versatile intermediate in general organic chemical synthesis.
What is the CAS number and chemical formula for (R)-5-Acetoxy-1-chlorohexane?
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The CAS number is 154885-34-4, and its linear chemical formula is CH3CO2CH(CH3)[(CH2)4Cl].
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-5-Acetoxy-1-chlorohexane with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the main safety concerns when handling (R)-5-Acetoxy-1-chlorohexane?
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This compound carries a Warning signal word and is associated with hazards including harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and is suspected of causing cancer (H351). Appropriate personal protective equipment, including eyeshields and gloves, is essential. Please consult the Safety Data Sheet for full details.
How is (R)-5-Acetoxy-1-chlorohexane typically packed and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures appropriate packaging for safe handling, transport, and export of (R)-5-Acetoxy-1-chlorohexane according to international regulations.
How can I request a sample or quote for (R)-5-Acetoxy-1-chlorohexane?
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To request a sample or a quotation for (R)-5-Acetoxy-1-chlorohexane, please contact our sales department through the website or by phone.
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