(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine
(R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine (CAS: 960128-64-7) is a chiral organophosphorus compound with the molecular formula C22H22NP and a molecular weight of 331.39 g/mol. It serves as a valuable ligand and catalyst component in asymmetric synthesis. This compound is essential for researchers and chemists involved in developing stereoselective reactions, particularly in the pharmaceutical and fine chemical industries.
- Synonyms
- 4-tetrahydronaphthalen-1-amine,960128-64-7, C22H22NP
Asymmetric Catalysis
This chiral phosphine ligand is instrumental in developing enantioselective catalytic systems. It is employed in transition metal catalysis to facilitate stereospecific bond formations.
Chiral Ligand Synthesis
It acts as a building block for more complex chiral ligands and auxiliaries used in asymmetric organic synthesis. Its structure provides a rigid chiral backbone for catalysis.
Pharmaceutical Intermediate Development
Utilised in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). Its application aids in producing specific stereoisomers required for drug efficacy and safety.
Research and Development
A key reagent for academic and industrial research laboratories exploring novel synthetic methodologies and stereoselective transformations.
| Molecular weight | 331.39 |
|---|---|
| Empirical formula | C22H22NP |
| Assay | 97% |
| Optical activity | [α]22/D −55.0°, c = 0.5 in chloroform |
| Melting point | 120-127 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Transport (UN / ADR) | UN 3335 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in the development of stereoselective reactions and the synthesis of chiral intermediates.
What are the CAS number and formula for this chemical?
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The CAS number is 960128-64-7, and its empirical formula (Hill notation) is C22H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, or EP grade. For specific batch requirements, please contact us.
How should (R)-8-(Diphenylphosphino)-1,2,3,4-tetrahydronaphthalen-1-amine be handled safely?
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This compound is a Warning, classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment (PPE), ensure good ventilation, and avoid contact with skin, eyes, and clothing. Always consult the Safety Data Sheet (SDS) before use.
How is this chemical packed and shipped?
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Products are carefully packed according to international shipping regulations. We export globally; please contact us for specific shipping and handling queries.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please use the 'Request a Quote' or 'Contact Us' form on our website, providing the product name and CAS number.
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