(R)-Binam-P
(R)-Binam-P, CAS 74974-14-4, is a chiral phosphine ligand with the molecular formula C44H34N2P2 and a molecular weight of 652.70. It is a crucial reagent in asymmetric synthesis, particularly in metal-catalyzed reactions. This compound is widely employed for its ability to induce enantioselectivity, making it invaluable in the synthesis of chiral molecules for pharmaceuticals and fine chemicals.
- IUPAC
- (R)-2,2′-Bis(diphenylphosphinoamino)-1,1′-binaphthyl
Asymmetric Catalysis
(R)-Binam-P serves as a chiral ligand in various transition metal-catalyzed asymmetric reactions. It is particularly effective in enantioselective transformations, enabling the synthesis of chiral compounds with high optical purity.
Hydrogenation Reactions
This phosphine ligand is utilized in asymmetric hydrogenation processes. It facilitates the stereoselective reduction of prochiral substrates, leading to enantiomerically enriched products, critical for pharmaceutical development.
Synthesis of Chiral Intermediates
As a chiral auxiliary and catalyst component, (R)-Binam-P is instrumental in constructing complex chiral molecules. It is applied in the synthesis of key intermediates for active pharmaceutical ingredients (APIs) and other high-value fine chemicals.
| Molecular weight | 652.70 |
|---|---|
| Empirical formula | C44H34N2P2 |
| Melting point | 151-156 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-Binam-P used for?
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(R)-Binam-P is primarily used as a chiral phosphine ligand in asymmetric synthesis and catalysis, particularly in asymmetric hydrogenation reactions to produce enantiomerically enriched compounds.
What is the CAS number and molecular formula for (R)-Binam-P?
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The CAS number for (R)-Binam-P is 74974-14-4, and its molecular formula is C44H34N2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-Binam-P as a research-grade chemical. The specific purity and assay are available upon request or via the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-Binam-P be handled and stored?
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Handle (R)-Binam-P with appropriate personal protective equipment, including gloves, eye protection, and a lab coat, as it may cause skin, eye, and respiratory irritation (H315, H319, H335). Store in a well-ventilated area away from incompatible materials.
How is (R)-Binam-P packed and exported?
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(R)-Binam-P is carefully packaged to ensure safe transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
How can I request a sample or quote for (R)-Binam-P?
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To request a sample or a quote for (R)-Binam-P, please contact our sales department through the website or by phone, providing your specific requirements.
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