(S)-(−)-5-Hydroxymethyl-2(5H)-furanone
(S)-(−)-5-Hydroxymethyl-2(5H)-furanone (CAS: 78508-96-0; C5H6O3) is a chiral heterocyclic compound with a molecular weight of 114.10 g/mol. This furanone derivative serves as a valuable building block in asymmetric synthesis and chemical research. Its specific stereochemistry makes it useful for creating complex chiral molecules, particularly within pharmaceutical and fine chemical development.

Chiral Building Block
Utilised in the synthesis of enantiomerically pure compounds. Its defined stereocenter is crucial for building complex chiral molecules in pharmaceutical research and development.
Asymmetric Synthesis
Employed as a precursor or intermediate in asymmetric synthesis pathways. It enables the creation of specific enantiomers of target molecules, vital for drug discovery and fine chemical production.
Heterocyclic Chemistry
Serves as a versatile starting material for constructing more complex heterocyclic structures. Its furanone core can be modified to yield a range of derivatives for various chemical applications.
| Molecular weight | 114.10 |
|---|---|
| Empirical formula | C5H6O3 |
| Assay | ≥97.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −148±5°, c = 1.4% in H2O |
| Storage temperature | 2-8°C |
| Melting point | 40-44 °C41-43 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-5-Hydroxymethyl-2(5H)-furanone used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and heterocyclic chemistry for research and development purposes.
What is the CAS number and molecular formula?
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The CAS number is 78508-96-0 and the molecular formula is C5H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, or EP grade.
How should (S)-(−)-5-Hydroxymethyl-2(5H)-furanone be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Store at 2-8°C. The compound has a flash point of 113°C.
How is this chemical packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or a quotation for (S)-(−)-5-Hydroxymethyl-2(5H)-furanone.
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