(S)-(−)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
(S)-(−)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (CAS 53174-06-4) is a chiral building block with the molecular formula C14H18O4 and a molecular weight of 250.29 g/mol. This chroman derivative possesses the chiral centre characteristic of α-tocopherol. It is valuable in asymmetric synthesis and serves as a key intermediate in the preparation of complex organic molecules, particularly those with heterocyclic benzopyran structures.
- Synonyms
- 8-tetramethylchroman-2-carboxylic acidC14H18O4

Chiral Building Block
This compound serves as a crucial chiral building block in organic synthesis. Its defined stereochemistry makes it ideal for constructing complex molecules where specific enantiomeric forms are required.
Asymmetric Synthesis
Valuable in asymmetric synthesis, this molecule facilitates the creation of enantiomerically enriched products. Its structure is analogous to the chiral center found in vitamin E (α-tocopherol).
Heterocyclic Chemistry
As a derivative of benzopyran, it is employed in the synthesis of various heterocyclic compounds. This is particularly relevant in pharmaceutical and material science research.
| Molecular weight | 250.29 |
|---|---|
| Empirical formula | C14H18O4 |
| Assay | 98% |
| Optical activity | [α]26/D −65°, c = 1.2 in ethanol |
| Application | A chroman possessing the chiral center of α-tocopherol.1 |
| Melting point | 160 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and in the preparation of heterocyclic compounds, notably those related to benzopyrans and vitamin E analogs.
What are the CAS number and formula for this chemical?
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The CAS number is 53174-06-4, and its empirical formula is C14H18O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should (S)-(−)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid be handled?
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This chemical is a warning substance and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation.
How is this product packed and shipped?
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Products are carefully packed according to international shipping regulations. We are experienced global suppliers and exporters of fine chemicals.
How can I request a sample or quote for this chemical?
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To request a sample or a formal quotation, please contact our sales team through the website or by phone, providing the product name and CAS number.
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