(S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide
(S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (CAS 98674-86-3) is a chiral phosphoric acid derivative with the molecular formula C11H14ClO4P and a molecular weight of 276.65 g/mol. This compound serves as a valuable chiral building block in asymmetric synthesis. It is primarily employed for the efficient resolution of amines, amino acids, and amino alcohols, facilitating the separation of enantiomers in chemical synthesis.
- Synonyms
- 2-dioxaphosphorinane 2-oxide, 98674-86-3, C11H14ClO4P
Chiral Resolution Agent
This dioxaphosphorinane derivative is a potent chiral resolving agent. It effectively separates enantiomers of amines, amino acids, and amino alcohols through diastereomeric salt formation or other chiral recognition mechanisms.
Asymmetric Synthesis
As a chiral building block, it plays a crucial role in asymmetric synthesis. Its inherent chirality can be transferred or used to induce stereoselectivity in various chemical transformations, leading to enantiomerically enriched products.
Organic Synthesis Intermediate
This compound serves as an intermediate in the synthesis of complex organic molecules, particularly where stereochemical control is paramount. Its structure allows for further functionalization in multi-step synthetic routes.
| Molecular weight | 276.65 |
|---|---|
| Empirical formula | C11H14ClO4P |
| Assay | 97% |
| Optical activity | [α]22/D −46°, c = 1 in methanol |
| Storage temperature | 2-8°C |
| Application | Chiral phosphoric acid used for the resolution of amines, amino acids, and amino alcohols.1,2,3 |
| Melting point | 228-234 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide used for?
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(S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide (CAS 98674-86-3) is primarily used as a chiral resolving agent for amines, amino acids, and amino alcohols in asymmetric synthesis.
What are the CAS number and formula for this chemical?
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The CAS number is 98674-86-3 and the empirical formula is C11H14ClO4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This product is not represented as USP, BP, or EP grade.
What are the safety precautions when handling this chemical?
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This compound is a warning-level irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide.
How can I request a quote or sample?
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To request a quote or a sample of (S)-(−)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-oxide, please contact our sales team through the website or call us directly.
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