(S)-(−)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution
(S)-(−)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution (CAS: 312693-18-8) is an organozinc halide reagent with a molecular weight of 246.42. Supplied at 0.5 M in THF, this chiral compound is valuable in organic synthesis, particularly for asymmetric carbon-carbon bond formation. Its specific stereochemistry makes it a useful tool for constructing complex molecules with defined spatial arrangements, often employed in pharmaceutical and fine chemical research and development.
Asymmetric Synthesis
Used as a chiral nucleophile in organozinc additions to carbonyl compounds and imines, enabling the stereoselective formation of new carbon-carbon bonds.
Pharmaceutical Intermediate Synthesis
Facilitates the construction of chiral building blocks crucial for the development of active pharmaceutical ingredients (APIs) requiring specific stereoisomers.
Fine Chemical Manufacturing
Employed in multi-step syntheses of complex organic molecules where precise control over stereochemistry is paramount.
Catalysis Research
Investigated for its potential in catalytic processes, particularly in asymmetric catalysis for producing enantiomerically enriched compounds.
| Molecular weight | 246.42 |
|---|---|
| Linear formula | CH3O2CCH(CH3)CH2ZnBr |
| Density | 0.965 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution used for?
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This reagent is primarily used in asymmetric synthesis for creating chiral carbon-carbon bonds, particularly in the development of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for this compound?
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The CAS number is 312693-18-8, and its linear formula is CH3O2CCH(CH3)CH2ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a 0.5 M solution in THF. We do not claim USP, BP, EP, or pharmacopoeia grade; it is suitable for research and laboratory applications.
How should (S)-(−)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution be handled?
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This compound is highly flammable (Flash Point -17 °C) and may form explosive peroxides. It is also irritating to eyes and the respiratory tract and suspected of causing cancer. Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment. Store at 2-8°C.
How is this chemical shipped or exported?
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This product is classified under UN 2924, Hazard Class 8 (Corrosive), Subsidiary Hazard 3 (Flammable liquid), Packing Group II. TSS exports this chemical in compliance with all relevant international shipping regulations.
How can I request a quote or sample?
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Please contact our sales team via the website or direct inquiry to request a quotation or a sample of (S)-(−)-3-Methoxy-2-methyl-3-oxopropylzinc bromide solution.
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