(S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride
(S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride (CAS: 117160-99-3), a chiral amino alcohol with the molecular formula C6H11CH2CH(NH2)CH2OH·HCl and a molecular weight of 193.71 g/mol. This compound serves as a valuable building block in asymmetric synthesis. It is primarily utilised in the development and production of pharmaceutical intermediates, notably in the synthesis of renin inhibitors.
- IUPAC
- (S)-2-Amino-3-cyclohexylpropanol hydrochloride,3-Cyclohexyl-L-alaninol
- Synonyms
- (S)-2-Amino-3-cyclohexylpropanol hydrochloride3-Cyclohexyl-L-alaninol
Pharmaceutical Synthesis
This chiral amino alcohol is a key intermediate in the synthesis of various pharmaceutical compounds. Its specific stereochemistry makes it particularly useful in the preparation of complex molecules, including the synthesis of renin inhibitors.
Asymmetric Synthesis
As a chiral building block, (S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride is employed in asymmetric synthesis to introduce specific stereocentres into target molecules. This is crucial for the development of enantiomerically pure active pharmaceutical ingredients (APIs).
Organic Synthesis Intermediate
The compound functions as a versatile intermediate in broader organic synthesis. Its amino and hydroxyl functionalities allow for a range of chemical transformations, enabling the construction of diverse molecular architectures.
| Molecular weight | 193.71 |
|---|---|
| Linear formula | C6H11CH2CH(NH2)CH2OH·HCl |
| Assay | 97% |
| Optical activity | [α]20/D +2.6°, c = 1 in methanol |
| Application | Used in the synthesis of renin inhibitors.1 |
| Melting point | 230 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride used for?
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(S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride is used in chemical synthesis, particularly as a building block in asymmetric synthesis and in the preparation of pharmaceutical intermediates such as renin inhibitors.
What are the CAS number and chemical formula?
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The CAS number is 117160-99-3, and the chemical formula is C6H11CH2CH(NH2)CH2OH·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, or EP grade.
How should this chemical be handled and stored?
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This compound is an irritant to the skin, eyes, and respiratory tract (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure good ventilation. Store in a cool, dry place.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including (S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride, please use the contact form on our website or call our sales department.
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