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(S)-(+)-2-Amino-3-methyl-1-butanol

CAS 2026-48-4(CH3)2CHCH(NH2)CH2OHChemical Synthesis

(S)-(+)-2-Amino-3-methyl-1-butanol (CAS 2026-48-4) is a chiral amino alcohol with the linear formula (CH₃)₂CHCH(NH₂)CH₂OH and a molecular weight of 103.16 g/mol. This optically active compound is valuable in asymmetric synthesis. It serves as a key building block, reacting with aldehydes and nitriles to form imines and oxazolines, respectively, facilitating the stereoselective synthesis of complex molecules in organic chemistry.

IUPAC
L-Valinol
Synonyms
L-Valinol
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(S)-(+)-2-Amino-3-methyl-1-butanol ((CH3)2CHCH(NH2)CH2OH) — chemical structure, CAS 2026-48-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Asymmetric Synthesis

Serves as a chiral building block for stereoselective synthesis. It reacts with aldehydes to form imines and with nitriles to produce oxazolines, enabling enantioselective transformations.

Organic Synthesis Intermediate

A versatile intermediate in organic chemistry, this amino alcohol is utilised in the construction of more complex chiral molecules. Its defined stereochemistry is crucial for targeted synthesis.

Chiral Ligand Precursor

Can be employed in the synthesis of chiral ligands for asymmetric catalysis. The amino and alcohol functionalities offer sites for further chemical modification.

02 /Properties
Molecular weight103.16
Linear formula(CH3)2CHCH(NH2)CH2OH
Assay96%
Boiling point81 °C/8 mmHg(lit.)
Density0.926 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.4548(lit.)
Optical activity[α]25/D +10°, c = 10 in H2O
Melting point30-32 °C(lit.)
Optical purityee: 95% (GLC)
Storage temperature2-8°C
ApplicationReacts with aldehydes and nitriles to form imines1 and oxazolines,2 respectively, for asymmetric synthesis.
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H319Causes serious eye irritation

Precautionary statements

  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point78 °C / 172.4 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2026-48-4
MDL number
MFCD00064296
PubChem substance
24851236
Beilstein registry
1719137
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-2-Amino-3-methyl-1-butanol used for?

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This compound is primarily used in asymmetric synthesis. It reacts with aldehydes to form imines and with nitriles to produce oxazolines, which are important intermediates in stereoselective chemical reactions.

What is the CAS number and formula for (S)-(+)-2-Amino-3-methyl-1-butanol?

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The CAS number is 2026-48-4 and the linear formula is (CH₃)₂CHCH(NH₂)CH₂OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-2-Amino-3-methyl-1-butanol with an assay of 96%. This product is not represented as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling considerations for this chemical?

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This compound is classified as a Warning (GHS07) and is associated with hazard statement H319 (Causes serious eye irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in accordance with P305 + P351 + P338 precautionary statements (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).

How is (S)-(+)-2-Amino-3-methyl-1-butanol packed, shipped, and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter since 1998, ensures appropriate packing and adherence to all shipping regulations for international export of fine chemicals like (S)-(+)-2-Amino-3-methyl-1-butanol.

How can I request a sample or quote?

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To request a sample or a quote for (S)-(+)-2-Amino-3-methyl-1-butanol, please contact our sales team through the details provided on the Tech Serve Solutions website.

Need (S)-(+)-2-Amino-3-methyl-1-butanol in a specific grade or volume?