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Dorsomorphin

CAS 866405-64-3C24H25N5OCell Biology

Dorsomorphin (CAS: 866405-64-3) is a potent small molecule inhibitor of bone morphogenetic protein (BMP) signalling pathways. With the molecular formula C24H25N5O and a molecular weight of 399.49 g/mol, this compound is primarily utilized as a research tool in cell biology and cancer research. It selectively inhibits BMP receptor serine/threonine kinase activity, making it invaluable for studying BMP-dependent processes.

IUPAC
6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine,AMPK Inhibitor,Compound C
Synonyms
Compound C6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
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Dorsomorphin (C24H25N5O) — chemical structure, CAS 866405-64-3; Life Science, fine chemical supplied by Tech Serve Solutions
BMPs and ReceptorsBioactive Small MoleculesCancer MetabolismCancer ResearchCell BiologyCytokines and Growth FactorsCytokinesGrowth Factors and Hormones
01 /Applications

BMP Signalling Research

Dorsomorphin is a key inhibitor used to investigate the diverse roles of BMP signalling in developmental biology, stem cell differentiation, and tissue regeneration. Its specific action allows researchers to dissect the downstream effects of BMP pathway modulation.

Cancer Metabolism Studies

This compound serves as a valuable probe for exploring the relationship between BMP signalling and cancer metabolism, particularly the Warburg effect. It aids in understanding how these pathways influence cellular energy production and tumour growth.

Cell Biology Investigations

As a bioactive small molecule, Dorsomorphin is employed in fundamental cell biology research to study cell fate decisions, proliferation, and apoptosis. Its application helps elucidate complex cellular mechanisms and signalling cascades.

02 /Properties
Molecular weight399.49
Empirical formulaC24H25N5O
Assay≥98% (HPLC)
Formpowder
Colourwhite to beige
SolubilityDMSO: >2 mg/mL (warmed)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H332Harmful if inhaled

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22
Safety statements (S)36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
866405-64-3
MDL number
MFCD08705402
05 /Additional specifications
Storage Conditionprotect from light
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Dorsomorphin used for?

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Dorsomorphin is used as a research tool in cell biology and cancer research to inhibit bone morphogenetic protein (BMP) signalling pathways, investigate the Warburg effect, and study cell fate decisions.

What is the CAS number and formula for Dorsomorphin?

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The CAS number for Dorsomorphin is 866405-64-3, and its empirical formula is C24H25N5O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Dorsomorphin with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should Dorsomorphin be handled safely?

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Dorsomorphin is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Handle with appropriate personal protective equipment, including a dust mask (N95 US equivalent), eyeshields, and gloves, in a well-ventilated area.

How is Dorsomorphin packed, shipped, and exported?

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Dorsomorphin is typically supplied as a white to beige powder. It requires storage at 2-8°C, protected from light. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations.

How can I request a sample or quote for Dorsomorphin?

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To request a sample or quote for Dorsomorphin, please contact our sales team through the website or by calling us directly. Specify the required quantity and your shipping destination.

Need Dorsomorphin in a specific grade or volume?