Domoic acid

CAS 14277-97-5C15H21NO6Cell Biology

Domoic acid (CAS: 14277-97-5, C15H21NO6) is a neurotoxic amino acid produced by certain algae and a potent agonist for AMPA and kainate receptors. It plays a significant role in neuroscience research, particularly in studies of excitotoxicity and synaptic plasticity. This compound is also investigated for its properties as a toxin, with implications for marine biotoxins and food safety. Tech Serve Solutions supplies Domoic acid for research applications.

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Domoic acid (C15H21NO6) — chemical structure, CAS 14277-97-5; Life Science, fine chemical supplied by Tech Serve Solutions

AMPA/Kainate AgonistsAlgaeBioactive Small MoleculesCell BiologyDIG-DYExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmission

01 /Applications

Neuroscience Research

Domoic acid is widely used as a tool in neuroscience to induce excitotoxicity and study neuronal damage. It serves as a potent agonist for ionotropic glutamate receptors, specifically AMPA and kainate subtypes.

Cellular Signaling Studies

Investigate the mechanisms of cell signaling pathways affected by excitatory amino acids. Domoic acid helps researchers understand receptor function and downstream cellular responses in neurons.

Marine Toxin Research

This compound is a naturally occurring marine biotoxin, and its study is crucial for understanding the ecological impact and public health risks associated with algal blooms and contaminated seafood.

02 /Properties

Molecular weight	311.33
Empirical formula	C15H21NO6
Assay	≥90% (HPLC)
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22
Safety statements (S)	36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

14277-97-5

MDL number

MFCD06795841

PubChem substance

24894006

Beilstein registry

46376

05 /Additional specifications

Gene Information	human ... GRIK1(2897)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Domoic acid used for?

Domoic acid is primarily used in neuroscience research to study excitotoxicity, receptor function (AMPA/Kainate), and neuronal damage. It is also studied as a marine biotoxin.

What are the CAS number and chemical formula for Domoic acid?

The CAS number for Domoic acid is 14277-97-5, and its chemical formula is C15H21NO6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Domoic acid with a purity of ≥90% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Domoic acid be handled and stored safely?

Handle Domoic acid with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. It is classified as harmful if swallowed, in contact with skin, or if inhaled. Store at -20°C.

How is Domoic acid packed, shipped, and exported?

Domoic acid is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions in compliance with all relevant regulations for chemical substances.