(S)-(+)-2-Amino-1-propanol
(S)-(+)-2-Amino-1-propanol (CAS: 2749-11-3), with the formula CH3CH(NH2)CH2OH and a molecular weight of 75.11 g/mol, is a chiral amino alcohol. This optically active compound, exhibiting an optical rotation of [α]20/D +18°, serves as a valuable chiral building block in organic synthesis. It is particularly noted for its ability to react with aryl nitriles to form oxazolines, which are key intermediates in palladium-catalyzed allylic substitution reactions.
- IUPAC
- L-Alaninol
- Synonyms
- L-Alaninol
Chiral Building Block
Utilised in asymmetric synthesis, this optically pure amino alcohol provides a defined stereochemical centre for the construction of complex molecules.
Oxazoline Synthesis
Reacts with aryl nitriles to form oxazolines, which are crucial intermediates in palladium-catalyzed reactions, particularly in allylic substitution.
Pharmaceutical Intermediate
Its chiral nature and reactive functional groups make it a useful precursor in the synthesis of pharmacologically active compounds.
| Molecular weight | 75.11 |
|---|---|
| Linear formula | CH3CH(NH2)CH2OH |
| Assay | 98% |
| Boiling point | 72-73 °C/11 mmHg(lit.) |
| Density | 0.965 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4498(lit.) |
| Optical activity | [α]20/D +18°, neat |
| Optical purity | ee: 97% (GLC) |
| Storage temperature | 2-8°C |
| Application | Reacts with aryl nitriles to form oxazolines1,2,3 which are useful in Pd-catalyzed allylic substitution.2,3 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 63 °C / 145.4 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Amino-1-propanol used for?
+
(S)-(+)-2-Amino-1-propanol is used as a chiral building block in organic synthesis, particularly for forming oxazolines which are intermediates in palladium-catalyzed allylic substitution reactions.
What is the CAS number and formula for (S)-(+)-2-Amino-1-propanol?
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The CAS number is 2749-11-3 and the chemical formula is CH3CH(NH2)CH2OH.
What grade and purity does Tech Serve Solutions supply for (S)-(+)-2-Amino-1-propanol?
+
Tech Serve Solutions supplies (S)-(+)-2-Amino-1-propanol with an assay of 98% and optical purity of ee: 97%. This product is not represented as USP, BP, or EP grade.
What are the safety and handling requirements for (S)-(+)-2-Amino-1-propanol?
+
(S)-(+)-2-Amino-1-propanol is classified as Danger, with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face protection and chemical-resistant gloves, must be used. Handle in a well-ventilated area. Store at 2-8°C.
How is (S)-(+)-2-Amino-1-propanol packed, shipped, and exported?
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Specific packaging, shipping, and export details are available upon request, adhering to all relevant transport regulations, including UN 2735 classification.
How can I request a quote or sample of (S)-(+)-2-Amino-1-propanol?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team through our website or by phone.
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