(S)-(−)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane
(S)-(−)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane (CAS 274674-22-5) is a chiral amine with the molecular formula (CH3)2CHCH2CH(NH2)C(F)(C6H5)2 and a molecular weight of 271.37 g/mol. This organic building block is valuable in asymmetric synthesis and general chemical synthesis. It is supplied by Tech Serve Solutions with an assay of 98% and high optical purity, making it suitable for demanding research and development applications.
- Synonyms
- (CH3)2CHCH2CH(NH2)C(F)(C6H5)2

Chiral Building Block
This compound serves as a crucial chiral building block in the synthesis of complex organic molecules. Its defined stereochemistry allows for the stereoselective construction of target compounds, vital in pharmaceutical research.
Asymmetric Synthesis
As an amine with specific stereochemical properties, it is employed in asymmetric synthesis methodologies. It can be used as a chiral auxiliary or a precursor to chiral catalysts, facilitating enantioselective transformations.
Organic Synthesis Intermediate
It functions as an intermediate in multi-step organic synthesis pathways. The presence of the amine and fluoro-diphenyl moieties offers versatile reactivity for further functionalization.
| Molecular weight | 271.37 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(NH2)C(F)(C6H5)2 |
| Assay | 98% |
| Optical activity | [α]20/D −50°, c = 1 in chloroform |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 86-89 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane primarily used for?
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(S)-(−)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic synthesis.
What are the CAS number and molecular formula?
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The CAS number is 274674-22-5. The linear formula is (CH3)2CHCH2CH(NH2)C(F)(C6H5)2, with a molecular weight of 271.37 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98% and an optical purity (ee) of 99% by HPLC. It is not represented as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is a warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, and ensure adequate ventilation. Avoid breathing dust.
How is this chemical exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product can be exported worldwide, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for (S)-(−)-2-Amino-1-fluoro-4-methyl-1,1-diphenylpentane.
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