(S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane
(S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane (CAS 290352-01-1) is a chiral fluorinated building block with the molecular formula (CH3)2CHCH(NH2)C(C6H5)2F and a molecular weight of 257.35 g/mol. This amine derivative is valuable in asymmetric synthesis, serving as a key intermediate for creating complex organic molecules. Its unique structure, featuring a fluorine atom and stereogenic center, makes it highly sought after in advanced chemical research and development.
- Synonyms
- (CH3)2CHCH(NH2)C(C6H5)2F

Asymmetric Synthesis
This compound serves as a chiral building block in stereoselective synthesis, enabling the construction of enantiomerically pure target molecules critical for pharmaceuticals and agrochemicals.
Fluorinated Organic Synthesis
The presence of a fluorine atom makes it an important intermediate for introducing fluorinated moieties into organic structures, impacting their electronic and pharmacokinetic properties.
Pharmaceutical Intermediate
Utilised in the development of novel drug candidates, where its specific chiral and fluorinated characteristics can contribute to therapeutic efficacy and metabolic stability.
Research and Development
A versatile reagent for academic and industrial research laboratories exploring new synthetic methodologies and molecular architectures.
| Molecular weight | 257.35 |
|---|---|
| Linear formula | (CH3)2CHCH(NH2)C(C6H5)2F |
| Assay | 97% |
| Optical activity | [α]20/D −45°, c = 1 in chloroform |
| Melting point | 54-57 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane used for?
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(S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane is primarily used as a chiral building block in asymmetric synthesis and for the introduction of fluorinated groups in organic molecules, particularly in pharmaceutical research and development.
What are the CAS number and formula for this compound?
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The CAS number is 290352-01-1, and its linear formula is (CH3)2CHCH(NH2)C(C6H5)2F.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a purity of 97% (assay). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust or vapours. It is classified as an irritant to skin, eyes, and respiratory system (H315, H319, H335).
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant international shipping.
How can I request a sample or quote?
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Please contact our sales team directly through our website or via the provided contact information to request a sample or a formal quotation for (S)-(−)-2-Amino-1-fluoro-3-methyl-1,1-diphenylbutane.
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