(S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol
(S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol (CAS 78603-95-9) is a chiral amino alcohol with the linear formula (CH3)2CHCH(NH2)C(C6H5)2(OH) and a molecular weight of 255.35 g/mol. This white to off-white crystalline solid is a valuable building block in asymmetric synthesis. Its specific stereochemistry and functional groups make it suitable for various applications in organic synthesis, particularly in the preparation of enantiomerically pure compounds.
- IUPAC
- (S)-2-Amino-1,1-diphenyl-3-methyl-1-butanol,1,1-Diphenyl-L-valinol
- Synonyms
- (CH3)2CHCH(NH2)C(C6H5)2(OH)(S)-2-Amino-1,1-diphenyl-3-methyl-1-butanol1,1-Diphenyl-L-valinol
Chiral Auxiliary in Asymmetric Synthesis
As a chiral amino alcohol, (S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol can serve as a chiral auxiliary to induce stereoselectivity in various organic reactions. It is used to control the formation of specific stereoisomers in the synthesis of complex molecules.
Precursor for Chiral Ligands
The compound's structure makes it a suitable precursor for synthesizing chiral ligands used in asymmetric catalysis. These ligands can coordinate with metal centres to create enantioselective catalysts for a wide range of transformations.
Building Block for Pharmaceutical Intermediates
Its defined stereochemistry and functional groups are leveraged in the multi-step synthesis of pharmaceutical intermediates. It contributes to the construction of stereochemically complex active pharmaceutical ingredients (APIs).
Organic Synthesis Reagent
This amino alcohol functions as a versatile organic building block for creating more complex molecular architectures. Researchers utilise it in academic and industrial settings for developing novel synthetic methodologies and compounds.
| Molecular weight | 255.35 |
|---|---|
| Linear formula | (CH3)2CHCH(NH2)C(C6H5)2(OH) |
| Assay | 98% |
| Optical activity | [α]20/D −132°, c = 1 in chloroform |
| Melting point | 95-99 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol primarily used for?
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(S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol is primarily used as a chiral building block in asymmetric synthesis, acting as a chiral auxiliary or a precursor for chiral ligands in the preparation of enantiomerically pure compounds and pharmaceutical intermediates.
What is the CAS number and linear formula for this chemical?
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The CAS number is 78603-95-9, and the linear formula is (CH3)2CHCH(NH2)C(C6H5)2(OH).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Amino-3-methyl-1,1-diphenyl-1-butanol with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this compound?
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This compound is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid dust formation. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We ensure compliant packaging and shipping procedures for international destinations.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department through the website or by telephone, providing the product name and CAS number.
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