(S)-(−)-2-Acetoxysuccinic anhydride
(S)-(−)-2-Acetoxysuccinic anhydride (CAS 59025-03-5), a chiral building block with the molecular formula C6H6O5 and a molecular weight of 158.11 g/mol, is a key reagent in asymmetric synthesis. This compound, supplied by Tech Serve Solutions, serves as a valuable intermediate in organic synthesis, offering a defined stereochemical pathway for complex molecule construction. Its primary applications lie in the preparation of enantiomerically pure compounds.
- IUPAC
- (S)-3-Acetoxy-dihydro-2,5-furandione,O-Acetyl-L-malic anhydride

Chiral Synthesis Intermediate
Serves as a crucial chiral building block in the stereoselective synthesis of complex organic molecules and pharmaceutical intermediates. Its defined stereochemistry allows for precise control in synthetic routes.
Asymmetric Catalysis Research
Utilised in research settings for the development and application of asymmetric catalytic processes. It can be employed to introduce chirality or as a precursor to chiral ligands.
Preparation of Enantiopure Compounds
A key precursor for the synthesis of enantiomerically pure acids, alcohols, and other functionalized molecules, essential for the pharmaceutical and fine chemical industries.
| Molecular weight | 158.11 |
|---|---|
| Empirical formula | C6H6O5 |
| Assay | 98% |
| Optical activity | [α]20/D −27°, c = 1 in chloroform |
| Optical purity | ee: 98% (GLC) |
| Melting point | 54-56 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2-Acetoxysuccinic anhydride used for?
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(S)-(−)-2-Acetoxysuccinic anhydride is primarily used as a chiral building block in asymmetric synthesis and for the preparation of enantiopure compounds.
What is the CAS number and molecular formula for this compound?
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The CAS number is 59025-03-5 and the molecular formula is C6H6O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-2-Acetoxysuccinic anhydride with an assay of 98% and an optical purity of ee: 98%. This is a research/technical grade material, and we do not represent it as USP, BP, or EP grade.
How should (S)-(−)-2-Acetoxysuccinic anhydride be handled?
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This compound is a warning-level chemical that can cause skin, eye, and respiratory irritation (H315-H319-H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn during handling. Ensure adequate ventilation.
Is (S)-(−)-2-Acetoxysuccinic anhydride a controlled substance?
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The provided data does not indicate that (S)-(−)-2-Acetoxysuccinic anhydride is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(−)-2-Acetoxysuccinic anhydride, adhering to all necessary shipping and export regulations.
How can I request a sample or quote for (S)-(−)-2-Acetoxysuccinic anhydride?
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Please contact our sales team via the website or direct inquiry to request a sample or a quotation for (S)-(−)-2-Acetoxysuccinic anhydride.
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