(RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline
(RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline (CAS: 149245-03-4) is a chiral phosphine ligand with the molecular formula C31H22NP and a molecular weight of 439.49 g/mol. This compound is a valuable building block and catalyst component, primarily utilised in organic synthesis, particularly in cross-coupling reactions. Its unique structure facilitates sophisticated chemical transformations, making it a key reagent for researchers and industrial chemists.
- IUPAC
- (+/-)-QUINAP,QUINAP
Catalysis
This phosphine ligand is employed as a crucial component in homogeneous catalysis, particularly for transition metal-catalyzed reactions such as cross-coupling (e.g., Suzuki, Buchwald-Hartwig). It can enhance reaction efficiency and selectivity.
Organic Synthesis
As a sophisticated building block, it enables the construction of complex organic molecules. Its application is significant in research and development for creating novel chemical entities.
Ligand Design
The compound serves as a precursor or a direct chiral auxiliary in the design and synthesis of new ligands for asymmetric catalysis, aiding in the development of stereoselective synthetic methodologies.
| Molecular weight | 439.49 |
|---|---|
| Empirical formula | C31H22NP |
| Assay | 95% |
| Composition | carbon, 81.7-87.7% elemental analysis |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline used for?
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This compound is primarily used as a ligand in catalysis, particularly for transition metal-catalyzed cross-coupling reactions, and as a building block in complex organic synthesis.
What are the CAS number and formula for (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline?
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The CAS number is 149245-03-4, and the molecular formula is C31H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling this chemical?
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This compound is classified as Warning (GHS07) and is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment in a well-ventilated area.
How is (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline packed, shipped, and exported?
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Tech Serve Solutions can expertly pack, ship, and export (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline globally, adhering to all necessary regulations.
How can I request a sample or quote for this chemical?
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To request a sample or obtain a quote for (RS)-1-(2-Diphenylphosphino-1-naphthyl)isoquinoline, please contact our sales team through the website or by phone.
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