(S)-1-(Diphenylphosphino)-3-methyl-2-butylamine
(S)-1-(Diphenylphosphino)-3-methyl-2-butylamine (CAS: 146476-37-1; Formula: C17H22NP; Molar Mass: 271.34 g/mol) is a chiral phosphine ligand. It is recognised for its utility in asymmetric catalysis and as a building block in complex organic synthesis. This compound finds application in catalysing reactions requiring specific stereochemical control, contributing to the efficient production of enantiomerically pure substances.
- IUPAC
- (S)-1-(Diphenylphosphino)-3-methylbutan-2-amine

Asymmetric Catalysis
This chiral phosphine ligand is employed in various metal-catalysed asymmetric transformations. It facilitates the synthesis of enantiomerically enriched products crucial for pharmaceuticals and fine chemicals.
Organic Synthesis
It serves as a valuable reagent and building block in the construction of complex organic molecules. Its specific structure allows for targeted stereochemical outcomes in synthetic pathways.
Ligand Development
The compound is used in the development and study of novel phosphine ligands for transition metal catalysis. Its unique steric and electronic properties can influence catalyst activity and selectivity.
| Molecular weight | 271.34 |
|---|---|
| Empirical formula | C17H22NP |
| Assay | 97% |
| Density | 1.050 g/mL at 25 °C |
| Refractive index | n20/D 1.597 |
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-(Diphenylphosphino)-3-methyl-2-butylamine used for?
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This compound is primarily used as a chiral phosphine ligand in asymmetric catalysis and as a building block in organic synthesis, particularly for creating enantiomerically pure substances.
What is the CAS number and chemical formula for this compound?
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The CAS number is 146476-37-1 and the chemical formula is C17H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 97%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-1-(Diphenylphosphino)-3-methyl-2-butylamine be handled safely?
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When handling, wear protective gloves and eye protection (P280). In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338). If exposed or concerned, immediately call a poison centre or doctor (P310).
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this compound.
How can I request a quote or sample?
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Please contact our sales team via our website or direct email to request a quotation or to inquire about sample availability.
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