(S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride
(S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride (CAS 1366421-67-1) is a chiral organocatalyst belonging to the class of cyclopropenimines, often referred to as "superbases." With a molecular weight of 582.30 g/mol, this compound is utilized in asymmetric synthesis for its potent basicity. It facilitates enantioselective proton transfer reactions, aiding in the production of optically enriched compounds vital for drug discovery and development.
- IUPAC
- (βS)-β-[[2,3-bis(dicyclohexylamino)-2-cyclopropen-1-ylidene]amino]-benzenepropanol hydrochloride (1:1),Dicyclohexyl cyclopropenimine,Lambert Cyclopropenimine Catalyst
- Synonyms
- C36H56ClN3O(βS)-β-[[2,3-bis(dicyclohexylamino)-2-cyclopropen-1-ylidene]amino]-benzenepropanol hydrochloride (1:1)Dicyclohexyl cyclopropenimineLambert Cyclopropenimine Catalyst
Enantioselective Organocatalysis
This chiral cyclopropenimine acts as a powerful Brønsted base catalyst, enabling the enantioselective synthesis of chiral molecules. Its high basicity and tunable structure make it effective for a variety of proton transfer reactions.
Chiral Pharmaceutical Ingredient Synthesis
The compound's ability to catalyze asymmetric reactions is crucial for the synthesis of optically pure pharmaceutical ingredients. This contributes to the development of new chiral drugs and simplifies complex synthetic routes.
Asymmetric Transition State Organisation
Its unique structure allows for precise organisation of the transition state in chemical reactions. This leads to high enantioselectivity, producing desired chiral compounds with high optical purity.
| Molecular weight | 582.30 |
|---|---|
| Empirical formula | C36H56ClN3O |
| Application | Chiral cyclopropenimines are highly effective new class of enantioselective Brønsted base catalysts, the so-called “superbases” for enantioselective organocatalysis. Due to the prevalence of chemical reactions involving proton transfer as a key mechanistic event, Brønsted bases have become indispensable tools for the practice of organic synthetic chemistry, capable of catalyzing proton transfer reactions enantioselectively for the production of optically enriched products. Novel Brønsted bases provide potent yet tunable basicity to the acidity of a given substrate, are trivial to prepare, and offer unique opportunities for asymmetric transition state organization. The high basicity should allow them to catalyze a wide range of reactions (i.e. chiral pharmaceutical ingredients) and could lead to easier and faster syntheses of novel chiral compounds for drug discovery and other applications.2,3-bis(dialkylamino)cyclopropenimin |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-(2,3-Bis(dicyclohexylamino)cyclopropenimine)-3-phenylpropan-1-ol hydrochloride used for?
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This compound is primarily used as a chiral Brønsted base catalyst in enantioselective organocatalysis, particularly for reactions involving proton transfer and the synthesis of optically enriched compounds for applications such as chiral pharmaceutical ingredients.
What is the CAS number and formula for this product?
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The CAS number is 1366421-67-1. The empirical formula is C36H56ClN3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific grade and purity are available upon request; we do not represent this product as USP, BP, or EP grade unless explicitly stated in the product documentation.
What are the safety considerations for handling this chemical?
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This compound is classified under WGK 2 (Water Hazard Class 2) in Germany, indicating it is hazardous to aquatic life. Please refer to the Safety Data Sheet (SDS) for comprehensive handling, storage, and disposal information.
How is this chemical shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all international shipping and export regulations for hazardous materials.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales department through the 'Contact Us' section of our website, providing the product name and CAS number (1366421-67-1).
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