Ro 25-6981 maleate salt
Ro 25-6981 maleate salt (CAS: 1312991-76-6) is a chemical compound with the formula C22H29NO2 · C4H4O4 and a molecular weight of 455.54 g/mol. It presents as a white to beige powder. This compound is recognised for its role in scientific research, particularly within the fields of cell biology, neuroscience, and the study of neurotransmission, serving as a valuable tool for investigating complex biological pathways.
- IUPAC
- 1-Piperidinepropanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, (αR,βS)-, (2Z)-2-butenedioate (1:1),[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate salt

Neuroscience Research
Ro 25-6981 maleate salt is utilised in neuroscience to investigate glutamatergic signaling pathways, specifically NMDA receptor activity. Its properties make it a relevant compound for studying mechanisms related to neuronal function and dysfunction.
Cell Signaling Studies
As a tool in cell biology, this compound aids in exploring cellular signalling cascades. Researchers use it to understand how cells communicate and respond to stimuli, contributing to the broader field of cell physiology.
Neurotransmission Investigations
This substance is employed to study the intricate processes of neurotransmission. Its application helps elucidate the roles of specific receptor antagonists in modulating synaptic activity and neuronal communication.
| Molecular weight | 455.54 |
|---|---|
| Empirical formula | C22H29NO2 · C4H4O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: soluble2 mg/mL (clear solution, warmed) |
| Optical activity | [α]/D +15 to +22°, c = 1 in methanol |
| Storage temperature | 2-8°C |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 36/37/38-50 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ro 25-6981 maleate salt used for?
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Ro 25-6981 maleate salt is primarily used in scientific research for investigating neuroscience, cell signaling, and neurotransmission, particularly relating to NMDA receptor activity.
What is the CAS number and formula for Ro 25-6981 maleate salt?
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The CAS number is 1312991-76-6 and the empirical formula is C22H29NO2 · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ro 25-6981 maleate salt with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Ro 25-6981 maleate salt be handled?
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Ro 25-6981 maleate salt is classified with GHS07 and GHS09 symbols, carrying a 'Warning' signal word. It has hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), H335 (may cause respiratory irritation), and H400 (very toxic to aquatic life). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release into the environment. Store desiccated at 2-8°C.
How is Ro 25-6981 maleate salt shipped?
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Ro 25-6981 maleate salt is shipped as UN 3077, Class 9, Packing Group III, suitable for a chemical that is environmentally hazardous. Global export services are available from TSS.
How can I request a sample or quote for Ro 25-6981 maleate salt?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or direct contact channels, providing the product name and CAS number.
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