2-Bromo-4-fluoroanisole
2-Bromo-4-fluoroanisole (CAS: 452-08-4), with the molecular formula BrC6H3(F)OCH3 and a molecular weight of 205.02 g/mol, is a fluorinated organic building block. This compound serves as a key intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique structure, featuring both bromine and fluorine substituents on an anisole core, allows for diverse chemical transformations and the introduction of specific functionalities into target molecules.

Pharmaceutical Intermediate
2-Bromo-4-fluoroanisole is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its reactive sites enable its incorporation into complex molecular structures, contributing to the development of novel therapeutic agents.
Agrochemical Synthesis
This compound finds application in the creation of new agrochemical products, such as pesticides and herbicides. The presence of fluorine can enhance the biological activity and stability of the final agrochemical compounds.
Research and Development
As a versatile building block, 2-Bromo-4-fluoroanisole is employed in academic and industrial research laboratories for exploring new synthetic routes and developing novel organic compounds with potential applications in various fields.
| Molecular weight | 205.02 |
|---|---|
| Linear formula | BrC6H3(F)OCH3 |
| Assay | 96% |
| Boiling point | 89 °C/1 mmHg(lit.) |
| Density | 1.581 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.545(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4-fluoroanisole used for?
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2-Bromo-4-fluoroanisole is primarily used as an intermediate in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and other novel organic compounds in research and development settings.
What is the CAS number and molecular formula of 2-Bromo-4-fluoroanisole?
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The CAS number for 2-Bromo-4-fluoroanisole is 452-08-4, and its molecular formula is BrC6H3(F)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4-fluoroanisole with an assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should 2-Bromo-4-fluoroanisole be handled safely?
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2-Bromo-4-fluoroanisole is a warning substance classified with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and suitable gloves, should be worn. Ensure adequate ventilation or use a respirator.
Can Tech Serve Solutions export 2-Bromo-4-fluoroanisole?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Bromo-4-fluoroanisole.
How can I request a quote or sample for 2-Bromo-4-fluoroanisole?
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To request a quote or sample for 2-Bromo-4-fluoroanisole, please contact our sales team through our website or by phone.
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