Ro 25-6981 hydrochloride hydrate
Ro 25-6981 hydrochloride hydrate (CAS: 919289-58-0) is a chemical compound with the formula C22H29NO2 · HCl · xH2O and a molecular weight of 375.93 g/mol (anhydrous basis). This white powder is primarily utilised in research settings, particularly within cell biology and neuroscience, for investigating ion channels and neurotransmission. It serves as a valuable tool for studying NMDA receptor modulators and related cellular signalling pathways.
- IUPAC
- [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate
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Neuroscience Research
Ro 25-6981 hydrochloride hydrate is employed in neuroscience research to investigate the function of NMDA receptors and their role in neurotransmission. Its properties make it useful for studying excitotoxicity and related neurological processes.
Cell Signaling Studies
This compound is a valuable reagent for understanding cell signaling pathways, specifically those involving ionotropic glutamate receptors. Researchers utilise it to explore the mechanisms of neuronal communication and signal transduction.
Ion Channel Modulation
As a modulator of ion channels, Ro 25-6981 hydrochloride hydrate aids in the study of ionotropic glutamate receptor function. It helps elucidate the complex interactions within neuronal networks.
| Molecular weight | 375.93 (anhydrous basis) |
|---|---|
| Empirical formula | C22H29NO2 · HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >20 mg/mL |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GRIN2B(2904) |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ro 25-6981 hydrochloride hydrate used for?
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Ro 25-6981 hydrochloride hydrate is primarily used in research settings, particularly within cell biology and neuroscience, for studying ion channels, neurotransmission, NMDA receptor modulators, and related cellular signalling pathways.
What is the CAS number and formula for Ro 25-6981 hydrochloride hydrate?
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The CAS number for the anhydrous form is 919289-58-0. The empirical formula is C22H29NO2 · HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ro 25-6981 hydrochloride hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Ro 25-6981 hydrochloride hydrate be handled?
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Ro 25-6981 hydrochloride hydrate is classified with GHS07 symbol and 'Warning' signal word, with hazard statements H315, H319, and H335. Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is Ro 25-6981 hydrochloride hydrate packed and shipped?
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This product is supplied as a white powder and should be stored under desiccated conditions. It is available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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Please contact our sales team or use the online enquiry form to request a quote or a sample of Ro 25-6981 hydrochloride hydrate.
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