(R)-(–)-VAPOL hydrogenphosphate
(R)-(–)-VAPOL hydrogenphosphate (CAS: 871130-18-6) is a chiral phosphoric acid with the empirical formula C40H25O4P and a molecular weight of 600.60. This compound serves as a valuable chiral Bronsted acid catalyst. It is primarily utilised in asymmetric synthesis, particularly in catalysing specific organic reactions that require high stereoselectivity. Its well-defined chiral structure makes it an important reagent in the development of complex molecules.
- IUPAC
- (R)-2,2′-Diphenyl-3,3′-biphenanthryl-4,4′-diyl phosphate,(R)-VAPOL phosphoric acid,18-Hydroxy-8,9-diphenyl-diphenanthro[4,3-d:3′,4′-f][1,3,2]dioxaphosphepin-18-oxide
Chiral Bronsted Acid Catalysis
This compound functions as a potent chiral Bronsted acid catalyst. It is particularly effective in promoting asymmetric reactions, enabling the synthesis of enantiomerically enriched products.
Addition of Sulfonamides to Imines
A key application is its use in the catalysed addition of sulfonamides to Boc-activated aryl imines. This reaction proceeds with high stereoselectivity, yielding desired chiral intermediates.
Asymmetric Synthesis Reagent
As a chiral catalyst, it is instrumental in various asymmetric synthesis strategies. It facilitates the creation of specific stereoisomers, which is crucial in pharmaceutical and fine chemical synthesis.
| Molecular weight | 600.60 |
|---|---|
| Empirical formula | C40H25O4P |
| Application | Useful chiral Bronsted acid catalyst in the addition of sulfonamides to Boc-activated aryl imines.6 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(–)-VAPOL hydrogenphosphate used for?
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(R)-(–)-VAPOL hydrogenphosphate is used as a chiral Bronsted acid catalyst in asymmetric synthesis, notably in the addition of sulfonamides to Boc-activated aryl imines.
What is the CAS number and formula for (R)-(–)-VAPOL hydrogenphosphate?
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The CAS number is 871130-18-6 and the empirical formula is C40H25O4P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(–)-VAPOL hydrogenphosphate as a research-grade chemical. We do not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for (R)-(–)-VAPOL hydrogenphosphate?
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This compound is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate personal protective equipment should be used, and handling should occur in a well-ventilated area, following standard laboratory safety protocols for hazardous chemicals.
How is (R)-(–)-VAPOL hydrogenphosphate packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships (R)-(–)-VAPOL hydrogenphosphate according to international regulations for chemical exports, ensuring product integrity and safety during transit.
How can I request a sample or quote for (R)-(–)-VAPOL hydrogenphosphate?
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To request a sample or a quotation for (R)-(–)-VAPOL hydrogenphosphate, please contact our sales team via the website or email. Please include your specific requirements and shipping details.
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