(R)-(+)-Indoline-2-carboxylic acid
(R)-(+)-Indoline-2-carboxylic acid (CAS: 98167-06-7; Formula: C9H9NO2; MW: 163.17) is a chiral building block vital for asymmetric synthesis. This indoline derivative serves as a key intermediate in the preparation of complex molecules, particularly in the fields of medicinal chemistry and organocatalysis. Its specific stereochemistry makes it valuable for introducing chirality into target compounds, enabling the development of stereoselective pharmaceuticals and advanced materials.
- IUPAC
- (R)-(+)-2,3-Dihydroindole-2-carboxylic acid
- Synonyms
- (R)-(+)-2,3-Dihydroindole-2-carboxylic acid
Asymmetric Synthesis
Utilised as a chiral building block to introduce stereospecificity in the synthesis of complex organic molecules. Its defined R-configuration is crucial for developing enantiomerically pure compounds.
Medicinal Chemistry
Serves as an intermediate in the synthesis of novel drug candidates. The indoline scaffold is present in various biologically active compounds, making this acid a valuable starting material.
Organocatalysis
Functions as a precursor for proline-based organocatalysts. These catalysts are employed in various asymmetric transformations, offering metal-free catalytic solutions.
Research and Development
A key reagent for academic and industrial research laboratories exploring new synthetic methodologies and developing novel chiral compounds.
| Molecular weight | 163.17 |
|---|---|
| Empirical formula | C9H9NO2 |
| Assay | ≥97.0% |
| Optical activity | [α]/D +11.0±1°, c = 0.3 in methanol |
Hazard statements
- H317May cause an allergic skin reaction
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 43-48/22-62 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-Indoline-2-carboxylic acid used for?
+
(R)-(+)-Indoline-2-carboxylic acid is primarily used in asymmetric synthesis as a chiral building block and as an intermediate in medicinal chemistry and organocatalysis.
What are the CAS number and formula for (R)-(+)-Indoline-2-carboxylic acid?
+
The CAS number is 98167-06-7 and the empirical formula is C9H9NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(+)-Indoline-2-carboxylic acid with an assay of ≥97.0%. This is a technical/research grade material and TSS does not represent it as USP/BP/EP.
What are the key safety concerns when handling this chemical?
+
This compound is classified with GHS07 and GHS08 symbols and a Warning signal word. It may cause an allergic skin reaction (H317) and is suspected of damaging fertility or the unborn child (H361). Appropriate personal protective equipment, including gloves and eye protection, should be worn, and handling should occur in a well-ventilated area.
How is (R)-(+)-Indoline-2-carboxylic acid packed and shipped?
+
Products are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a sample or quote for (R)-(+)-Indoline-2-carboxylic acid?
+
Please contact our sales team through the website or direct email to request a sample or obtain a quotation.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis