(R)-(+)-Glycidol
(R)-(+)-Glycidol (CAS 57044-25-4, C3H6O2) is a chiral epoxide with a molecular weight of 74.08 g/mol. This optically active compound, with a specific rotation of +15°, serves as a valuable chiral building block in organic synthesis. Its primary application lies in the stereoselective construction of complex molecules, including its documented use in the synthesis of marine natural products. Supplied with a minimum assay of 97%, it is essential for advanced chemical research and development.
- IUPAC
- (R)-(+)-Oxirane-2-methanol
- Synonyms
- (R)-(+)-Oxirane-2-methanol
Chiral Building Block
Serves as a key chiral synthon in asymmetric synthesis, enabling the stereocontrolled introduction of epoxide functionalities. It has been documented for use in the construction of complex molecular architectures.
Natural Product Synthesis
Utilised in the synthesis pathway of natural products, such as a furanocembrane marine natural product. Its chiral nature is critical for achieving the correct stereochemistry in the target molecule.
Epoxyvinyl Iodide Intermediate
A specific application involves its role in creating an epoxyvinyl iodide intermediate, a crucial step in multi-stage synthetic sequences.
| Molecular weight | 74.08 |
|---|---|
| Empirical formula | C3H6O2 |
| Assay | 97% |
| Boiling point | 56-57 °C/11 mmHg(lit.) |
| Density | 1.116 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.43(lit.) |
| Optical activity | [α]23/D +15°, neat |
| Optical purity | ee: 98% (GLC) |
| Storage temperature | −20°C |
| Impurities tested | <3% dichloromethane |
| Application | Chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product.1 |
Hazard statements
- H242Heating may cause a fire
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
- H341Suspected of causing genetic defects
- H350May cause cancer
- H360F
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | E,T |
| Risk statements (R) | 45-60-2-21/22-23-34 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-Glycidol used for?
+
(R)-(+)-Glycidol is primarily used as a chiral building block in asymmetric synthesis, particularly in the construction of complex molecules such as marine natural products. It is employed to create specific intermediates like epoxyvinyl iodides.
What is the CAS number and chemical formula for (R)-(+)-Glycidol?
+
The CAS number for (R)-(+)-Glycidol is 57044-25-4, and its chemical formula is C3H6O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(+)-Glycidol with a minimum assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should (R)-(+)-Glycidol be handled and stored?
+
(R)-(+)-Glycidol is classified as dangerous. It is flammable, causes severe skin burns and eye damage, and is toxic if inhaled. It is also suspected of causing genetic defects, cancer, and damage to fertility. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, and a respirator. Store refrigerated at -20°C.
Is (R)-(+)-Glycidol a controlled substance?
+
The provided safety data does not indicate that (R)-(+)-Glycidol is a controlled substance. However, users should always verify local regulations.
How are (R)-(+)-Glycidol products shipped?
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(R)-(+)-Glycidol is shipped according to international regulations for hazardous materials. Specific packaging and transport details are available upon request.
How can I request a quote or sample for (R)-(+)-Glycidol?
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To request a quote or sample of (R)-(+)-Glycidol, please contact our sales team through the website or by phone. Please specify the quantity required.
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