(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol
(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (CAS 948595-00-4) is a sophisticated chiral organocatalyst with the molecular formula C21H15F12NO and a molecular weight of 525.33 g/mol. This proline-derived compound is highly valued in asymmetric synthesis for its ability to promote enantioselective transformations. Its unique structure, featuring bulky trifluoromethylphenyl groups, enables precise control over stereochemistry in various chemical reactions, making it an indispensable tool for complex molecule synthesis.
- IUPAC
- (R)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine
- Synonyms
- 948595-00-4, C21H15F12NO, (R)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine
![(R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol (C21H15F12NO) — chemical structure, CAS 948595-00-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F948595-00-4.png&w=3840&q=75)
Asymmetric Organocatalysis
This compound serves as a potent chiral catalyst in asymmetric synthesis, facilitating the enantioselective formation of stereocenters in organic molecules. It is particularly effective in reactions requiring high optical purity.
Chiral Ligand Development
The molecule's structure makes it a valuable precursor or component in the design of chiral ligands for transition metal catalysis. It can influence the stereochemical outcome of metal-catalyzed reactions.
Pharmaceutical Intermediate Synthesis
Its application in asymmetric synthesis is crucial for the stereoselective preparation of chiral pharmaceutical intermediates, ensuring the production of enantiomerically pure active pharmaceutical ingredients (APIs).
Advanced Chemical Synthesis
Used in complex organic synthesis, this catalyst enables the development of novel synthetic routes for advanced materials and fine chemicals where precise stereochemical control is paramount.
| Molecular weight | 525.33 |
|---|---|
| Empirical formula | C21H15F12NO |
| Assay | ≥99.0% (HPLC)≥99.0% |
| Optical purity | ee: ≥99.0% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 113-117 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol primarily used for?
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This compound is primarily used as a chiral catalyst in asymmetric synthesis to promote enantioselective chemical transformations.
What is the CAS number and formula for this chemical?
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The CAS number is 948595-00-4, and its empirical formula is C21H15F12NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥99.0% (HPLC) and an optical purity of ee: ≥99.0% (HPLC). We do not represent it as USP, BP, or EP grade.
How should (R)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol be handled and stored?
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This compound should be handled with appropriate personal protective equipment, including eyeshields, gloves, and a P1 or N95 respirator. It requires storage at 2-8°C.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, including this product.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team through the website or via email, providing the product name and CAS number.
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