(R)-(+)-3,3-Difluoro-1,2-heptanediol

CAS 158358-96-4CH3(CH2)3CF2CH(OH)CH2OHChemical Synthesis

(R)-(+)-3,3-Difluoro-1,2-heptanediol (CAS: 158358-96-4) is a chiral fluorinated diol with a molecular weight of 168.18 g/mol. Its structure contains a difluoromethylene group and two hydroxyl functionalities, making it a valuable building block. This compound is primarily utilized in asymmetric synthesis and organic chemical synthesis, serving as a key intermediate for creating more complex molecules with specific stereochemistry, particularly in pharmaceutical research and development.

Synonyms: 158358-96-4, CH3(CH2)3CF2CH(OH)CH2OH

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(R)-(+)-3,3-Difluoro-1,2-heptanediol (CH3(CH2)3CF2CH(OH)CH2OH) — chemical structure, CAS 158358-96-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building BlocksPolyols

01 /Applications

Chiral Building Block in Organic Synthesis

This enantiomerically pure diol serves as a versatile building block for constructing complex chiral molecules. Its difluoro-moiety can introduce unique electronic and conformational properties into target compounds, often found in medicinal chemistry and materials science.

Intermediate for Fluorinated Compounds

The presence of the CF2 group makes it useful in the synthesis of specialised fluorinated organic compounds. These are of interest in pharmaceuticals, agrochemicals, and advanced materials due to fluorine's ability to modulate lipophilicity, metabolic stability, and binding affinity.

Research and Development

Used in academic and industrial research laboratories for exploring novel synthetic routes and developing new chemical entities. Its specific stereochemistry and functional groups enable precise molecular design.

02 /Properties

Molecular weight	168.18
Linear formula	CH3(CH2)3CF2CH(OH)CH2OH
Assay	95%
Boiling point	130-132 °C/30 mmHg(lit.)
Density	0.783 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.419(lit.)
Optical activity	[α]22/D +13°, c = 1.3 in chloroform

03 /Safety & handling

Flash point	113 °C / 235 °F
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

158358-96-4

MDL number

MFCD01321332

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-(+)-3,3-Difluoro-1,2-heptanediol used for?

(R)-(+)-3,3-Difluoro-1,2-heptanediol is used as a chiral building block in organic synthesis, particularly for creating complex fluorinated molecules relevant to pharmaceutical research and development.

What are the CAS number and chemical formula for this compound?

The CAS number is 158358-96-4, and its linear formula is CH3(CH2)3CF2CH(OH)CH2OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-(+)-3,3-Difluoro-1,2-heptanediol with an assay of 95%. We do not represent this product as USP, BP, or EP grade.

What are the safety concerns associated with this chemical?

This compound has a flash point of 113 °C (235 °F) and is classified under WGK Germany 3, indicating it is hazardous to water. Always consult the Safety Data Sheet (SDS) and handle with appropriate personal protective equipment in a well-ventilated area.

How is this product typically packed, shipped, and exported?

Products are carefully packed according to international shipping regulations to ensure integrity during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally.