(R)-(−)-2-Phenylglycine chloride hydrochloride
(R)-(−)-2-Phenylglycine chloride hydrochloride (CAS: 39878-87-0) is a chiral organic compound with the linear formula C6H5CH(NH2)COCl·HCl and a molecular weight of 206.07 g/mol. It serves as a valuable building block in chemical synthesis and peptide chemistry. This compound is particularly useful for introducing unnatural amino acid derivatives into complex molecules, aiding in the development of novel pharmaceuticals and research chemicals.
- IUPAC
- (R)-α-Aminophenylacetyl chloride hydrochloride,D−(−)−α-Phenylglycine chloride hydrochloride
- Synonyms
- (R)-α-Aminophenylacetyl chloride hydrochlorideD−(−)−α-Phenylglycine chloride hydrochloride
Chiral Building Block in Organic Synthesis
(R)-(−)-2-Phenylglycine chloride hydrochloride is a key intermediate for the stereoselective synthesis of complex organic molecules. Its chiral nature allows for the construction of specific enantiomers, crucial in pharmaceutical development.
Peptide Synthesis
This compound acts as a derivative of unnatural amino acids, enabling the incorporation of phenylglycine moieties into peptide chains. This is valuable for creating modified peptides with altered biological activities or stability.
Chemical Biology Research
It is utilised in chemical biology to synthesise probes and modified biomolecules. These tools help researchers investigate biological pathways and protein functions.
| Molecular weight | 206.07 |
|---|---|
| Linear formula | C6H5CH(NH2)COCl·HCl |
| Assay | 97% |
| Optical activity | [α]29/D −116°, c = 6 in 1 M HCl |
| Melting point | 117 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 150 °C / 302 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34-42 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Phenylglycine chloride hydrochloride used for?
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It is primarily used as a chiral building block in organic synthesis, for peptide synthesis involving unnatural amino acids, and in chemical biology research.
What is the CAS number and chemical formula for this product?
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The CAS number is 39878-87-0 and the linear formula is C6H5CH(NH2)COCl·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(−)-2-Phenylglycine chloride hydrochloride be handled safely?
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This compound is dangerous; it causes severe skin burns and eye damage (H314), is harmful if swallowed (H302), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). It may also cause an allergic skin reaction (H317). Always use appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, and handle in a well-ventilated area.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions exports and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a sample or quote?
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Please contact our sales team to request a sample or a quotation for (R)-(−)-2-Phenylglycine chloride hydrochloride.
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