(R)-(−)-2-Phenylglycinol
(R)-(−)-2-Phenylglycinol (CAS: 56613-80-0) is a chiral amino alcohol with the molecular formula C<sub>6</sub>H<sub>5</sub>CH(NH<sub>2</sub>)CH<sub>2</sub>OH and a molecular weight of 137.18 g/mol. This compound serves as a valuable chiral building block in organic synthesis. It is primarily utilised in the preparation of chiral imines and oxazolidines, which are key intermediates in the synthesis of complex molecules such as α-trifluoromethylproline.
- IUPAC
- (R)-2-Amino-2-phenylethanol,D-(−)-α-Phenylglycinol
- Synonyms
- (R)-2-Amino-2-phenylethanolD-(−)-α-Phenylglycinol
Chiral Synthesis Intermediate
(R)-(−)-2-Phenylglycinol is employed in stereoselective synthesis to introduce chirality. It reacts with carbonyl compounds to form imines or oxazolidines, which can then undergo further transformations.
Preparation of Chiral Amines
This amino alcohol can be a precursor for the synthesis of other chiral amines or their derivatives, finding use in pharmaceutical and fine chemical research.
Amino Acid Derivative Synthesis
As an amino acid derivative, it is a key component in constructing molecules with specific stereochemical requirements, including modified amino acids and peptides.
| Molecular weight | 137.18 |
|---|---|
| Linear formula | C6H5CH(NH2)CH2OH |
| Assay | 98% |
| Optical activity | [α]24/D −31.7°, c = 0.76 in 1 M HCl |
| Optical purity | ee: 99% (GLC) |
| Application | Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of α-trifluoromethylproline.1 |
| Melting point | 75-77 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Phenylglycinol primarily used for?
+
(R)-(−)-2-Phenylglycinol is primarily used as a chiral building block in organic synthesis, particularly for preparing chiral imines, oxazolidines, and intermediates like α-trifluoromethylproline.
What is the CAS number and chemical formula for (R)-(−)-2-Phenylglycinol?
+
The CAS number is 56613-80-0 and the linear chemical formula is C<sub>6</sub>H<sub>5</sub>CH(NH<sub>2</sub>)CH<sub>2</sub>OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(−)-2-Phenylglycinol with an assay of 98% and optical purity of ee: 99%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for (R)-(−)-2-Phenylglycinol?
+
Handle (R)-(−)-2-Phenylglycinol with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. The substance has a WGK rating of 3, indicating it is hazardous to water.
How is (R)-(−)-2-Phenylglycinol packed, shipped, and exported?
+
(R)-(−)-2-Phenylglycinol is carefully packed according to industry standards for safe handling and transit. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for (R)-(−)-2-Phenylglycinol?
+
To request a sample or a quote for (R)-(−)-2-Phenylglycinol, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis