(R)-(−)-2-Phenylglycine methyl ester hydrochloride
(R)-(−)-2-Phenylglycine methyl ester hydrochloride (CAS: 19883-41-1), with the linear formula C6H5CH(NH2)CO2CH3·HCl and a molecular weight of 201.65 g/mol, is a chiral unnatural amino acid derivative. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and the development of novel chemical entities. Its defined stereochemistry makes it suitable for applications requiring specific molecular configurations.

Chiral Building Block in Organic Synthesis
Utilised as a chiral synthon for the construction of complex organic molecules. Its enantiomeric purity is critical for asymmetric synthesis pathways, enabling the formation of stereochemically defined products.
Peptide Chemistry and Drug Discovery
Incorporated into peptide chains as an unnatural amino acid to modify biological activity, stability, or conformation. It is instrumental in research for novel pharmaceuticals and peptidomimetics.
Chemical Biology Research
Employed in studies investigating biochemical pathways and molecular interactions where specific chiral structures are required. It aids in the design of probes and inhibitors for biological targets.
| Molecular weight | 201.65 |
|---|---|
| Linear formula | C6H5CH(NH2)CO2CH3·HCl |
| Assay | ≥95% |
| Optical activity | [α]20/D −118°, c = 1 in H2O |
| Melting point | 189-191 °C(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Phenylglycine methyl ester hydrochloride used for?
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This compound is primarily used as a chiral building block in chemical synthesis, particularly in peptide chemistry and for the development of unnatural amino acid derivatives in drug discovery and chemical biology research.
What is the CAS number and formula for (R)-(−)-2-Phenylglycine methyl ester hydrochloride?
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The CAS number is 19883-41-1 and the linear formula is C6H5CH(NH2)CO2CH3·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-2-Phenylglycine methyl ester hydrochloride with an assay of ≥95%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(−)-2-Phenylglycine methyl ester hydrochloride be handled?
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This compound is classified as an irritant (H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes.
Is (R)-(−)-2-Phenylglycine methyl ester hydrochloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(−)-2-Phenylglycine methyl ester hydrochloride. We can arrange shipment worldwide.
How can I request a sample or quote?
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To request a sample or a quote for (R)-(−)-2-Phenylglycine methyl ester hydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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