(R)-(−)-2-Methylpiperazine
(R)-(−)-2-Methylpiperazine (CAS: 75336-86-6, Formula: C5H12N2) is a chiral building block with a molecular weight of 100.16 g/mol. Supplied at 97% purity, this heterocyclic compound is a valuable synthon in the synthesis of complex organic molecules. Its applications are primarily focused within chemical synthesis, particularly in the development of asymmetric compounds and pharmaceutical intermediates, including quinoline antibacterials.
Asymmetric Synthesis
Serves as a chiral building block for the stereoselective synthesis of complex molecules, enabling control over reaction stereochemistry.
Pharmaceutical Intermediates
A key synthon in the preparation of active pharmaceutical ingredients (APIs), notably used in the synthesis of quinoline antibacterials.
Heterocyclic Chemistry
Utilised in the construction of nitrogen-containing heterocyclic ring systems, offering a versatile scaffold for further chemical modification.
Organic Synthesis
Employed as a reagent in general organic synthesis for introducing chiral amine functionalities into target molecules.
| Molecular weight | 100.16 |
|---|---|
| Empirical formula | C5H12N2 |
| Assay | 97% |
| Optical activity | [α]20/D −16.5°, c = 5 in benzene |
| Application | Valuable synthon for quinoline antibacterials.1 |
| Melting point | 91-93 °C(lit.) |
Hazard statements
- H228Flammable solid
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 65 °C / 149 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Methylpiperazine used for?
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(R)-(−)-2-Methylpiperazine is primarily used as a valuable synthon for quinoline antibacterials and in asymmetric and general organic synthesis as a chiral building block.
What are the CAS number and formula for (R)-(−)-2-Methylpiperazine?
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The CAS number for (R)-(−)-2-Methylpiperazine is 75336-86-6, and its empirical formula is C5H12N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-2-Methylpiperazine with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations when handling (R)-(−)-2-Methylpiperazine?
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This compound is a flammable solid (H228) and an irritant to skin, eyes, and respiratory tract (H315, H319, H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (N100 or P3 filters), must be used. Handle in a well-ventilated area away from ignition sources.
How is (R)-(−)-2-Methylpiperazine shipped?
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(R)-(−)-2-Methylpiperazine is classified under UN 1325, Hazard Class 4.1, Packing Group II, indicating it is a flammable solid. TSS ensures all shipments comply with relevant international dangerous goods regulations for export.
How can I request a quote or sample?
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To request a quote or a sample of (R)-(−)-2-Methylpiperazine, please contact our sales team through the TSS website or via direct inquiry, providing your specific requirements and contact details.
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