(R)-(−)-2-Methylpyrrolidine
(R)-(−)-2-Methylpyrrolidine (CAS: 41720-98-3, C5H11N) is a valuable chiral heterocyclic building block. With a molecular weight of 85.15 g/mol, it is utilized in asymmetric synthesis and chemical manufacturing. Notably, it serves as a key component in the multi-kilogram synthesis of chiral naphthalenoid histamine receptor antagonists, highlighting its importance in complex organic chemistry research and development.
Chiral Auxiliary in Asymmetric Synthesis
As a chiral amine, (R)-(−)-2-Methylpyrrolidine can function as a chiral auxiliary or building block in enantioselective synthesis. Its defined stereochemistry is crucial for controlling the stereochemical outcome of reactions, leading to the formation of specific enantiomers.
Intermediate for Pharmaceutical Synthesis
This compound is employed in the synthesis of complex pharmaceutical agents. Its application in the multi-kilogram scale production of chiral naphthalenoid histamine receptor antagonists demonstrates its utility in creating pharmacologically active molecules.
Heterocyclic Compound Synthesis
As a substituted pyrrolidine, it is a useful starting material for constructing more elaborate heterocyclic structures. These structures are frequently found in biologically active compounds and advanced materials.
| Molecular weight | 85.15 |
|---|---|
| Empirical formula | C5H11N |
| Density | 0.842 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4353 |
| Storage temperature | 2-8°C |
| Application | Building block used in a multikilogram synthesis of a chiral naphthalenoid histamine receptor antagonist.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Methylpyrrolidine used for?
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(R)-(−)-2-Methylpyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of complex organic molecules, including pharmaceutical agents such as chiral naphthalenoid histamine receptor antagonists.
What are the CAS number and formula for (R)-(−)-2-Methylpyrrolidine?
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The CAS number for (R)-(−)-2-Methylpyrrolidine is 41720-98-3, and its molecular formula is C5H11N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-2-Methylpyrrolidine typically as a research or technical grade material. The exact assay and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product data.
How should (R)-(−)-2-Methylpyrrolidine be handled safely?
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(R)-(−)-2-Methylpyrrolidine is flammable and corrosive. Handle with appropriate personal protective equipment, including gloves, goggles, and face shields. Ensure adequate ventilation and avoid sources of ignition. Refer to the safety data sheet for comprehensive handling guidelines.
How is (R)-(−)-2-Methylpyrrolidine packed and shipped?
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(R)-(−)-2-Methylpyrrolidine is shipped according to international regulations for hazardous materials, including UN 2924 classification. Packaging is designed to maintain product integrity and safety during transit. We export globally.
How can I request a sample or quote for (R)-(−)-2-Methylpyrrolidine?
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To request a sample or a quote for (R)-(−)-2-Methylpyrrolidine, please contact our sales team through the website or by calling us directly. Provide your requirements, and we will respond promptly.
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