(R)-(−)-2-Methoxy-2-phenylethanol
(R)-(−)-2-Methoxy-2-phenylethanol (CAS: 17628-72-7), with the molecular formula C6H5CH(OCH3)CH2OH and a molecular weight of 152.19 g/mol, is a valuable chiral building block. This optically active alcohol is primarily utilised in asymmetric synthesis and organic synthesis for the construction of complex molecules. Its defined stereochemistry makes it an important intermediate in various chemical manufacturing processes.
- IUPAC
- (−)-β-Methoxyphenethyl alcohol
- Synonyms
- (−)-β-Methoxyphenethyl alcohol

Chiral Synthesis
(R)-(−)-2-Methoxy-2-phenylethanol serves as a crucial chiral building block in the synthesis of enantiomerically pure compounds. Its stereogenic centre is often incorporated into target molecules, directing stereoselective reactions.
Organic Synthesis Intermediate
This compound functions as a versatile intermediate in multi-step organic syntheses. The hydroxyl and methoxy ether functionalities offer diverse points for chemical modification and elaboration.
Asymmetric Catalysis Research
It can be employed in the development and study of asymmetric catalysts. Its chiral nature is fundamental for inducing stereoselectivity in catalytic transformations.
| Molecular weight | 152.19 |
|---|---|
| Linear formula | C6H5CH(OCH3)CH2OH |
| Assay | 98% |
| Boiling point | 65 °C/0.1 mmHg(lit.) |
| Density | 1.05 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.52(lit.) |
| Optical activity | [α]20/D −133°, c = 1 in acetone |
| Optical purity | ee: 99% (GLC) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Methoxy-2-phenylethanol used for?
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(R)-(−)-2-Methoxy-2-phenylethanol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in general organic synthesis.
What is the CAS number and formula for (R)-(−)-2-Methoxy-2-phenylethanol?
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The CAS number is 17628-72-7 and the molecular formula is C6H5CH(OCH3)CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-2-Methoxy-2-phenylethanol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(−)-2-Methoxy-2-phenylethanol be handled?
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Handle (R)-(−)-2-Methoxy-2-phenylethanol with appropriate personal protective equipment, including eyeshields and gloves. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. Ensure adequate ventilation and avoid breathing dust/fume/gas/mist/vapours/spray.
How is (R)-(−)-2-Methoxy-2-phenylethanol packed, shipped, and exported?
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(R)-(−)-2-Methoxy-2-phenylethanol is carefully packed for secure transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for (R)-(−)-2-Methoxy-2-phenylethanol?
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To request a sample or obtain a quote for (R)-(−)-2-Methoxy-2-phenylethanol, please contact our sales team through the website or by phone.
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