4-Nitroacetanilide
4-Nitroacetanilide (CAS: 104-04-1) is an organic compound with the molecular formula C8H8N2O3 and a molecular weight of 180.16 g/mol. This nitro compound serves as a valuable intermediate in chemical synthesis. Its applications include its use as a test substrate for hydrolysis studies and as a precursor for the synthesis of other organic molecules, notably 4-aminoacetanilide. Supplied by Tech Serve Solutions, it is available at 98% purity.
- IUPAC
- 4′-Nitroacetanilide,Acetic acid 4-nitroanilide
- Synonyms
- 4′-NitroacetanilideAcetic acid 4-nitroanilidep-Nitroacetanilide

Hydrolysis Studies
4-Nitroacetanilide has been employed as a substrate in kinetic studies to investigate hydrolysis reactions, with its progress typically monitored using UV spectroscopic methods. This application aids in understanding reaction mechanisms and rates.
Synthesis of 4-Aminoacetanilide
This compound is a direct precursor for the preparation of 4-aminoacetanilide. The reduction of the nitro group on 4-Nitroacetanilide yields the corresponding amine, a crucial step in the synthesis of various organic compounds.
Organic Synthesis Intermediate
As a functionalised aromatic compound, 4-Nitroacetanilide acts as a versatile building block in organic synthesis. Its nitro and acetamide groups allow for diverse chemical transformations, enabling the construction of more complex molecular structures.
| Molecular weight | 180.16 |
|---|---|
| Linear formula | CH3CONHC6H4NO2 |
| Assay | 98% |
| Application | 4-Nitroacetanilide was used as a test substrate and its hydrolysis was determined by UV spectroscopic measurements1. It was also used to prepare 4-aminoacetanilide2. |
| Melting point | 213-215 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitroacetanilide used for?
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4-Nitroacetanilide is used as a test substrate in hydrolysis studies and as a precursor for the synthesis of 4-aminoacetanilide and other organic compounds. It serves as a valuable intermediate in chemical synthesis.
What is the CAS number and molecular formula for 4-Nitroacetanilide?
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The CAS number for 4-Nitroacetanilide is 104-04-1, and its molecular formula is C8H8N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitroacetanilide with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling 4-Nitroacetanilide?
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4-Nitroacetanilide is classified as a warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be used.
How is 4-Nitroacetanilide packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details will be provided based on your order requirements and destination, adhering to all relevant transport regulations.
How can I request a sample or quote for 4-Nitroacetanilide?
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To request a sample or a quotation for 4-Nitroacetanilide, please contact our sales department through the website or by calling our office. Please include the product name and CAS number in your request.
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