(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (CAS: 15186-48-8) is a chiral aldehyde with the molecular formula C6H10O3 and a molecular weight of 130.14 g/mol. This versatile building block is essential in asymmetric synthesis, serving as a key reactant in various organic transformations. Its applications span the creation of complex molecules, including functionalized aziridines and specialized dyes, making it valuable for research and development in pharmaceuticals and materials science.
- IUPAC
- (R)-(+)-Glyceraldehyde acetonide,(R)-Isopropylideneglyceraldehyde,NSC 89869
- Synonyms
- 15186-48-8C6H10O3(R)-(+)-Glyceraldehyde acetonide(R)-IsopropylideneglyceraldehydeNSC 89869
Asymmetric Synthesis
Utilised as a chiral building block for stereoselective synthesis of complex organic molecules, contributing to the development of enantiomerically pure compounds.
Organic Reaction Reagent
Serves as a reactant in diverse organic transformations such as Henry condensation reactions, olefination, and aldol-type condensations, enabling the formation of various functional groups.
Synthesis of Functionalized Aziridines
Key intermediate in the synthesis of highly functionalized chiral aziridines, which are important motifs in medicinal chemistry and natural product synthesis.
Dye Synthesis
Employed in the synthesis of hydrophilic pyrazine dyes, finding application as exogenous fluorescent tracer agents in various biological and chemical studies.
| Molecular weight | 130.14 |
|---|---|
| Empirical formula | C6H10O3 |
| Boiling point | 139 °C(lit.) |
| Density | 1.045 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |
| Optical activity | [α]22/D +53.8°, c = 2 in chloroform |
| Storage temperature | −20°C |
| Application | Reactant involved in organic reactions including:• Henry condensation reactions1• Synthesis of highly functionalized chiral aziridines2• Olefination of aldehydes3• C-H oxidations4• Aldol-type condensations5• Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents6• Hosomi-Sakurai reactions7 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, participating in reactions like Henry condensation, olefination, and the synthesis of functionalized aziridines and fluorescent dyes.
What is the CAS number and formula for (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde?
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The CAS number is 15186-48-8 and the molecular formula is C6H10O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde be handled?
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Handle with appropriate personal protective equipment including eyeshields, gloves, and a half-mask respirator. It is a combustible liquid with a flash point of 62°C (143.6°F) and should be stored at -20°C.
How is this chemical shipped and exported?
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This chemical is shipped according to relevant regulations, classified under NA 1993 / PGIII. Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or obtain a quote for (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde.
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