(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine
(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine (CAS 442905-33-1), with a molecular formula of C46H50N2O4P2 and a molecular weight of 756.85, is a high-purity chiral ligand. This compound is instrumental in asymmetric synthesis, particularly in catalytic hydrogenation processes. Its specialized structure enables precise control over stereochemistry, making it valuable for creating enantiomerically pure compounds.
- IUPAC
- (R)-Xylyl-P-Phos
- Synonyms
- 6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine, C46H50N2O4P2, (R)-Xylyl-P-Phos
Asymmetric Hydrogenation
This ligand is employed as a chiral auxiliary in asymmetric hydrogenation reactions. It facilitates the stereoselective reduction of unsaturated substrates, leading to the formation of chiral products with high enantiomeric excess.
Chiral Catalyst Development
As a key component in chiral catalysts, (R)-Xylyl-P-Phos is crucial for developing advanced catalytic systems. Its unique phosphine structure contributes to the high activity and selectivity required in complex organic transformations.
Fine Chemical Synthesis
The compound serves as a valuable reagent in the synthesis of fine chemicals and pharmaceutical intermediates where stereochemical control is paramount. Its application ensures the production of desired enantiomers with high fidelity.
| Molecular weight | 756.85 |
|---|---|
| Empirical formula | C46H50N2O4P2 |
| Assay | 97% |
| Optical activity | [α]20/D +125°, c = 1 in chloroform |
| Application | Ligand employed in the asymmetic hydrogenation of |
| Melting point | 190-194 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine used for?
+
This compound is primarily used as a chiral ligand in asymmetric synthesis, particularly for asymmetric hydrogenation reactions.
What are the CAS number and molecular formula?
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The CAS number is 442905-33-1 and the molecular formula is C46H50N2O4P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine be handled?
+
This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields, gloves, and a dust mask (N95 US), and avoid breathing dust.
Is this chemical exported globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team through the website to request a quote or a sample of this product.
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