(5S)-5-(Hydroxymethyl)-3-[(1R)-1-phenylethyl]-2-oxazolidinone
(5S)-5-(Hydroxymethyl)-3-[(1R)-1-phenylethyl]-2-oxazolidinone (CAS: 480424-72-4) is a chiral oxazolidinone derivative with the molecular formula C12H15NO3 and a molecular weight of 221.25 g/mol. It is a valuable intermediate in asymmetric synthesis, particularly for creating enantiomerically pure compounds. Its defined stereochemistry makes it a key building block in the synthesis of complex organic molecules.
- IUPAC
- (S)-5-(Hydroxymethyl)-3-[(R)-α-methylbenzyl-2-oxazolidinone,3-(1′-(R)-α-Methylbenzyl)-5(S)-hydroxymethyl-oxazolidin-2-one
![(5S)-5-(Hydroxymethyl)-3-[(1R)-1-phenylethyl]-2-oxazolidinone (C12H15NO3) — chemical structure, CAS 480424-72-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-72-4.png&w=3840&q=75)
Chiral Auxiliary in Asymmetric Synthesis
This oxazolidinone derivative serves as an effective chiral auxiliary, enabling the stereoselective synthesis of complex organic molecules. It facilitates the introduction of chirality into target compounds with high enantiomeric excess.
Intermediate for Pharmaceutical Synthesis
Its defined stereochemistry and functional groups make it a suitable intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). It can be employed in the construction of chiral drug molecules.
Building Block for Fine Chemicals
The compound acts as a versatile building block in the synthesis of various fine chemicals. Its oxazolidinone core and chiral side chain offer opportunities for diverse chemical transformations.
| Molecular weight | 221.25 |
|---|---|
| Empirical formula | C12H15NO3 |
| Assay | 98% |
| Melting point | 116-120 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (5S)-5-(Hydroxymethyl)-3-[(1R)-1-phenylethyl]-2-oxazolidinone used for?
+
(5S)-5-(Hydroxymethyl)-3-[(1R)-1-phenylethyl]-2-oxazolidinone is primarily used as a chiral auxiliary in asymmetric synthesis and as an intermediate in the synthesis of pharmaceuticals and fine chemicals.
What are the CAS number and formula for this compound?
+
The CAS number is 480424-72-4, and the empirical formula (Hill notation) is C12H15NO3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound with an assay of 98%. It is not specified as USP, BP, or EP grade; TSS does not represent it as such.
What safety precautions should be taken when handling this chemical?
+
Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. Observe standard laboratory safety protocols.
Is this product available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be exported.
How can I request a sample or a quote?
+
To request a sample or a quote, please contact the Tech Serve Solutions sales team via the website or by phone, providing the product name and CAS number.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis