(±)-AMPA
(±)-AMPA (CAS 74341-63-2), with the molecular formula C7H10N2O4 and a molecular weight of 186.17 g/mol, is a white solid. This compound functions as an excitatory amino acid and a selective agonist for AMPA receptors. It is widely utilised in neuroscience research to study synaptic plasticity, learning, memory, and excitotoxicity in various experimental models.
- IUPAC
- (±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrate

Neuroscience Research Tool
(±)-AMPA is a valuable research chemical for investigating the function of AMPA receptors in the central nervous system. It is used to explore mechanisms related to synaptic transmission, neuronal excitability, and the pathophysiology of neurological disorders.
Studying Synaptic Plasticity
This compound serves as a pharmacological tool to induce and study long-term potentiation (LTP) and long-term depression (LTD) in brain slices and in vivo, which are cellular models for learning and memory.
Investigating Excitotoxicity
Due to its potent excitotoxic properties at high concentrations, (±)-AMPA is employed in experimental settings to model neuronal damage and explore potential neuroprotective strategies.
Receptor Pharmacology
Researchers utilize (±)-AMPA to characterise AMPA receptor subtypes and their roles in various physiological and pathological processes, contributing to a deeper understanding of neurotransmission.
| Molecular weight | 186.17 |
|---|---|
| Empirical formula | C7H10N2O4 |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble1 mg/mL (warm)0.1 M HCl: soluble3.5 mg/mL0.1 M NaOH: soluble4.3 mg/mLDMSO: soluble4.3 mg/mL1 M HCl: soluble50 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-AMPA used for?
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(±)-AMPA is primarily used as a research tool in neuroscience to study AMPA receptors, synaptic plasticity, learning, memory, and excitotoxicity. It acts as a selective agonist for AMPA receptors.
What is the CAS number and formula for (±)-AMPA?
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The CAS number for (±)-AMPA is 74341-63-2, and its molecular formula is C7H10N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-AMPA as a research grade chemical. The specific purity is typically >95% or >98%, as indicated on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (±)-AMPA be handled safely?
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Handle (±)-AMPA with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK-Germany 3, indicating a high hazard level.
How is (±)-AMPA packed and shipped?
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Products like (±)-AMPA are carefully packed in accordance with international shipping regulations for chemicals and exported globally by Tech Serve Solutions.
How can I request a sample or quote for (±)-AMPA?
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To request a sample or a quote for (±)-AMPA, please use the contact form on our website or contact our sales department directly.
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