(5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone
(5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone (CAS: 1287211-10-2, C5H6F3NO) is a chiral fluorinated building block. With a molecular weight of 153.10 g/mol, this compound is valuable in asymmetric synthesis and the construction of complex molecules. Its trifluoromethyl and pyrrolidinone moieties offer unique reactivity for advanced chemical research and development, particularly in creating novel heterocyclic compounds. TSS supplies this chemical for laboratory and research applications.
Chiral Building Block
Utilised as a key stereospecific precursor in the synthesis of enantiomerically pure compounds. Its defined stereochemistry is crucial for constructing complex chiral targets in medicinal chemistry and materials science.
Fluorinated Intermediate
Incorporates a trifluoromethyl group, imparting unique electronic and lipophilic properties. This makes it useful in developing new pharmaceuticals or agrochemicals where fluorine substitution is desired for enhanced efficacy or metabolic stability.
Heterocyclic Synthesis
Serves as a versatile starting material for the preparation of diverse fluorinated heterocyclic structures. The pyrrolidinone ring offers a scaffold for further functionalisation and elaboration.
Asymmetric Synthesis
Enables the introduction of chirality into molecules, facilitating the stereoselective synthesis of biologically active compounds. It is a valuable tool for researchers aiming to control molecular stereochemistry.
| Molecular weight | 153.10 |
|---|---|
| Empirical formula | C5H6F3NO |
| Assay | 97% |
| Melting point | 98-105 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone primarily used for?
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(5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone is primarily used as a chiral building block and fluorinated intermediate in asymmetric synthesis and the preparation of heterocyclic compounds for chemical research and development.
What are the CAS number and molecular formula for (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone?
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The CAS number for (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone is 1287211-10-2, and its molecular formula is C5H6F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone with an assay of 97%. This is a research grade material and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia standard.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection if needed) in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
How is (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone typically packed, shipped, and exported?
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TSS packages this chemical in appropriate containers for safe transport and export, adhering to all relevant shipping regulations for laboratory reagents.
How can I request a sample or quote for (5S)-(−)-5-(Trifluoromethyl)-2-pyrrolidinone?
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To request a sample or a quote, please contact the TSS sales department through the website or by calling our customer service line.
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