(R)-(−)-1-Cbz-3-pyrrolidinol
(R)-(−)-1-Cbz-3-pyrrolidinol (CAS: 100858-33-1, Formula: C12H15NO3) is a chiral pyrrolidine derivative supplied by Tech Serve Solutions. With a molecular weight of 221.25 g/mol, this compound serves as a valuable building block in asymmetric synthesis and complex chemical manufacturing. Its defined stereochemistry makes it crucial for constructing stereochemically pure molecules, particularly in the pharmaceutical and fine chemical industries. We supply this product at a minimum assay of 95%.
- IUPAC
- (R)-N-Z-3-Pyrrolidinol,(R)-1-Benzyloxycarbonyl-3-pyrrolidinol,(R)-1-Carbobenzoxy-3-pyrrolidinol
- Synonyms
- (R)-N-Z-3-Pyrrolidinol(R)-1-Benzyloxycarbonyl-3-pyrrolidinol(R)-1-Carbobenzoxy-3-pyrrolidinol
Chiral Building Block in Organic Synthesis
(R)-(−)-1-Cbz-3-pyrrolidinol is a key intermediate for introducing chirality into target molecules. Its protected hydroxyl group and pyrrolidine ring offer versatile reaction pathways for further functionalization in multi-step syntheses.
Pharmaceutical Intermediate
This compound is frequently utilised in the synthesis of active pharmaceutical ingredients (APIs) where precise stereochemical control is paramount. Its structure lends itself to the development of novel therapeutic agents.
Asymmetric Synthesis
The inherent chirality of (R)-(−)-1-Cbz-3-pyrrolidinol makes it an important reagent in asymmetric synthesis, enabling the creation of enantiomerically enriched products through stereoselective transformations.
Heterocyclic Chemistry
As a functionalised pyrrolidine, it is instrumental in the construction of more complex heterocyclic frameworks, which are common motifs in many biologically active compounds.
| Molecular weight | 221.25 |
|---|---|
| Empirical formula | C12H15NO3 |
| Assay | 95% |
| Melting point | 74-79 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1-Cbz-3-pyrrolidinol used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the preparation of complex organic molecules, including pharmaceuticals and fine chemicals.
What are the CAS number and formula for (R)-(−)-1-Cbz-3-pyrrolidinol?
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The CAS number is 100858-33-1 and the empirical formula is C12H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-1-Cbz-3-pyrrolidinol with a minimum assay of 95%. This is a technical/research grade material and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety concerns when handling (R)-(−)-1-Cbz-3-pyrrolidinol?
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This compound is classified under GHS06 with the signal word 'Danger'. It carries hazard statements H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a type P2 respirator, is essential.
How is (R)-(−)-1-Cbz-3-pyrrolidinol packed and shipped?
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Tech Serve Solutions exports (R)-(−)-1-Cbz-3-pyrrolidinol globally. Packaging adheres to stringent safety and regulatory standards for hazardous materials, including UN 2811 classification (Toxic solid, organic, n.o.s.). Specific packing details are available upon request.
How can I request a sample or quote for (R)-(−)-1-Cbz-3-pyrrolidinol?
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To request a sample or a quotation for (R)-(−)-1-Cbz-3-pyrrolidinol, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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