(R)-(−)-1-Cbz-3-aminopyrrolidine
(R)-(−)-1-Cbz-3-aminopyrrolidine (CAS: 122536-73-6; Formula: C12H16N2O2; MW: 220.27) is a chiral pyrrolidine derivative. This compound serves as a valuable building block in asymmetric synthesis and chemical research. Its structure, featuring a protected amine and a chiral centre, makes it suitable for the construction of complex organic molecules, particularly in pharmaceutical and agrochemical development. TSS supplies this reagent with an assay of 97%.
- IUPAC
- (R)-1-Benzyloxycarbonyl-3-aminopyrrolidine
Asymmetric Synthesis
As a chiral building block, (R)-(−)-1-Cbz-3-aminopyrrolidine is employed in stereoselective synthesis to introduce specific chirality into target molecules. It is useful in the development of enantiomerically pure pharmaceuticals.
Pharmaceutical Intermediate
This compound is a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its pyrrolidine core and protected amine functionality allow for diverse derivatization pathways.
Heterocyclic Chemistry
The pyrrolidine scaffold makes this compound a useful starting material for constructing more complex heterocyclic systems. It is fundamental in research exploring novel nitrogen-containing compounds.
Chemical Research and Development
Researchers utilize (R)-(−)-1-Cbz-3-aminopyrrolidine in exploring new synthetic methodologies and creating novel molecular architectures for various scientific investigations.
| Molecular weight | 220.27 |
|---|---|
| Empirical formula | C12H16N2O2 |
| Assay | 97% |
| Boiling point | 315 °C |
| Density | 1.155 g/mL at 25 °C |
| Refractive index | n20/D 1.548 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1-Cbz-3-aminopyrrolidine used for?
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(R)-(−)-1-Cbz-3-aminopyrrolidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules.
What are the CAS number and molecular formula of this compound?
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The CAS number for (R)-(−)-1-Cbz-3-aminopyrrolidine is 122536-73-6, and its molecular formula is C12H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-1-Cbz-3-aminopyrrolidine with an assay of 97%. This product is not represented as USP, BP, or EP grade.
What are the safety precautions when handling (R)-(−)-1-Cbz-3-aminopyrrolidine?
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This compound is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including gloves, eyeshields, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is (R)-(−)-1-Cbz-3-aminopyrrolidine packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports (R)-(−)-1-Cbz-3-aminopyrrolidine globally, adhering to all relevant regulations for chemical transport.
How can I request a sample or quote for (R)-(−)-1-Cbz-3-aminopyrrolidine?
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To request a sample or a quotation for (R)-(−)-1-Cbz-3-aminopyrrolidine, please contact our sales team through the website or by phone.
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