(R)-(−)-1,2-Propanediol
(R)-(−)-1,2-Propanediol (CAS: 4254-14-2) is a chiral diol with the molecular formula CH3CH(OH)CH2OH and a molecular weight of 76.09 g/mol. This optically active compound is primarily utilised as a valuable chiral building block in asymmetric synthesis and general chemical synthesis. Its specific stereochemistry makes it instrumental in the creation of enantiomerically pure target molecules across various research and development applications.
- IUPAC
- (R)-(−)-Propylene glycerol,(R)-(−)-Propylene glycol
- Synonyms
- (R)-(−)-Propylene glycerol(R)-(−)-Propylene glycol
Asymmetric Synthesis
Utilised as a chiral synthon for the stereoselective construction of complex organic molecules. Its defined stereocenter allows for the introduction of chirality in subsequent reaction steps, crucial for pharmaceutical and fine chemical development.
Chiral Building Block
Serves as a fundamental component in the synthesis of enantiomerically pure compounds. Its diol functionality offers versatile reaction pathways for derivatization and incorporation into larger molecular frameworks.
Organic Synthesis
A useful reagent in general organic synthesis, offering a readily available source of a chiral three-carbon unit. It can participate in a variety of reactions typical of diols, such as esterification, etherification, and oxidation.
| Molecular weight | 76.09 |
|---|---|
| Linear formula | CH3CH(OH)CH2OH |
| Assay | 96% |
| Boiling point | 186-188 °C/765 mmHg(lit.) |
| Density | 1.04 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.434(lit.) |
| Optical activity | [α]20/D −16.5°, neat |
| Optical purity | ee: 98% (GLC) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 103 °C / 217.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1,2-Propanediol primarily used for?
+
(R)-(−)-1,2-Propanediol is primarily used as a chiral building block in asymmetric synthesis and general chemical synthesis.
What are the CAS number and formula for (R)-(−)-1,2-Propanediol?
+
The CAS number for (R)-(−)-1,2-Propanediol is 4254-14-2 and its linear formula is CH3CH(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(−)-1,2-Propanediol with an assay of 96% and 98% optical purity (ee). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (R)-(−)-1,2-Propanediol be handled?
+
Handling requires appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Refer to the safety data sheet for detailed handling and hazard information. The flash point is 103 °C (217.4 °F).
Is (R)-(−)-1,2-Propanediol a controlled substance?
+
There is no information in the provided data to suggest that (R)-(−)-1,2-Propanediol is a controlled substance.
How is (R)-(−)-1,2-Propanediol packed and exported?
+
(R)-(−)-1,2-Propanediol is exported by Tech Serve Solutions and is available in various pack sizes suitable for laboratory and industrial use. Please contact us for specific packaging and shipping inquiries.
How can I request a quote or sample for (R)-(−)-1,2-Propanediol?
+
To request a quote or a sample of (R)-(−)-1,2-Propanediol, please contact our sales department through the website or via direct contact details provided.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis