(R)-(−)-1,3-Butanediol
(R)-(−)-1,3-Butanediol (CAS: 6290-03-5) is a chiral diol with the molecular formula C4H10O2 and a molar mass of 90.12 g/mol. This optically active compound, with a specific rotation of [α]21/D −31.0°, is a valuable building block in asymmetric synthesis. It serves as a key intermediate in the preparation of complex organic molecules, particularly in the pharmaceutical and fine chemical industries.
- Synonyms
- CH3CH(OH)CH2CH2OH(R)-1,3-Butanediol
Chiral Building Block
(R)-(−)-1,3-Butanediol is widely utilized as a chiral synthon in the synthesis of enantiomerically pure compounds. Its defined stereochemistry makes it ideal for constructing complex molecules where specific spatial arrangements are critical.
Asymmetric Synthesis
This polyol is instrumental in asymmetric synthesis, enabling the creation of chiral centres in target molecules. It is frequently employed in multi-step syntheses requiring high stereochemical control.
Organic Synthesis Intermediate
As a versatile organic building block, (R)-(−)-1,3-Butanediol participates in various organic transformations. It can be functionalised further for incorporation into diverse chemical structures.
| Molecular weight | 90.12 |
|---|---|
| Linear formula | CH3CH(OH)CH2CH2OH |
| Assay | 98% |
| Boiling point | 107-110 °C/23 mmHg(lit.) |
| Density | 1.005 g/mL at 25 °C(lit.) |
| Optical activity | [α]21/D −31.0°, c = 1 in ethanol |
| Optical purity | ee: 98% (GLC) |
| Vapour pressure | 0.06 mmHg (20 °C) |
| Vapour density | 3.1 (vs air) |
| Autoignition temp | 741 °F |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1,3-Butanediol primarily used for?
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It is primarily used as a chiral building block and intermediate in asymmetric synthesis and organic synthesis for creating enantiomerically pure compounds.
What are the CAS number and chemical formula for (R)-(−)-1,3-Butanediol?
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The CAS number is 6290-03-5 and the linear chemical formula is CH3CH(OH)CH2CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-1,3-Butanediol with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should (R)-(−)-1,3-Butanediol be handled safely?
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Handle with care, wearing appropriate personal protective equipment including eyeshields and gloves. Avoid breathing vapours or dust. It is classified as a skin, eye, and respiratory irritant (H315, H319, H335).
How is this product packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or a quote for (R)-(−)-1,3-Butanediol?
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Please contact our sales team directly via the website or by phone to request a sample or a quotation.
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