(R)-(+)-1,2-Dithiolane-3-pentanoic acid
(R)-(+)-1,2-Dithiolane-3-pentanoic acid (CAS: 1200-22-2) is a chiral organic compound with the molecular formula C8H14O2S2 and a molecular weight of 206.33 g/mol. This lipoic acid derivative is valuable in asymmetric synthesis and chemical research. Its specific stereochemistry makes it a useful building block for creating complex chiral molecules, particularly within pharmaceutical and fine chemical development. TSS supplies this compound for laboratory and industrial research applications.
- IUPAC
- (R)-6,8-Dithiooctanoic acid,(R)-6,8-Thioctic acid
- Synonyms
- (R)-6,8-Dithiooctanoic acid(R)-6,8-Thioctic acidC8H14O2S2

Chiral Building Block in Organic Synthesis
(R)-(+)-1,2-Dithiolane-3-pentanoic acid serves as a key chiral synthon for constructing stereochemically defined molecules. Its defined stereocentre is crucial for asymmetric synthesis strategies in the development of complex organic compounds, including pharmaceuticals and advanced materials.
Research in Asymmetric Synthesis
This compound is employed in academic and industrial research settings focused on asymmetric synthesis. Its unique dithiolane ring and pentanoic acid chain offer specific reactivity and stereochemical control for developing novel synthetic methodologies and target molecules.
Intermediate in Fine Chemical Production
As a heterocyclic building block, it can be utilised as an intermediate in the synthesis of fine chemicals. Its structure allows for diverse chemical modifications, facilitating the creation of specialised chemical entities for various downstream applications.
| Molecular weight | 206.33 |
|---|---|
| Empirical formula | C8H14O2S2 |
| Assay | 97% |
| Optical activity | [α]20/D +104°, c = 1 in chloroform |
| Melting point | 48-52 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1,2-Dithiolane-3-pentanoic acid used for?
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(R)-(+)-1,2-Dithiolane-3-pentanoic acid is primarily used as a chiral building block in asymmetric synthesis and as a research chemical in organic synthesis and fine chemical production.
What are the CAS number and formula for (R)-(+)-1,2-Dithiolane-3-pentanoic acid?
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The CAS number is 1200-22-2 and the empirical formula (Hill Notation) is C8H14O2S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1,2-Dithiolane-3-pentanoic acid with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-(+)-1,2-Dithiolane-3-pentanoic acid be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Ensure adequate ventilation. The compound has a flash point of >110 °C (>230 °F).
Is (R)-(+)-1,2-Dithiolane-3-pentanoic acid a controlled substance?
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The provided data does not indicate that (R)-(+)-1,2-Dithiolane-3-pentanoic acid is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is carefully packaged according to international shipping regulations for chemical export.
How can I request a sample or quote for (R)-(+)-1,2-Dithiolane-3-pentanoic acid?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (1200-22-2).
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