3-Methylindene-2-carboxylic acid
3-Methylindene-2-carboxylic acid (CAS: 34225-81-5) is an organic compound with the molecular formula C11H10O2 and a molecular weight of 174.20 g/mol. This carboxylic acid derivative serves as a valuable building block in organic synthesis. It is primarily utilised in research and development for the creation of complex molecules and has been employed in the synthesis of specific imaging probes and related chemical entities. Supplied by Tech Serve Solutions for laboratory and research applications.
Synthesis of Imaging Probes
3-Methylindene-2-carboxylic acid has been used as a precursor in the synthesis of LKS01-B650, an imaging probe designed for selective binding to the catalytically active LMP7 subunit of immunoproteasome within living cells.
Chemical Derivatization
The compound can be chemically modified, such as through reduction reactions. For instance, it has been reduced using sodium amalgam to yield 1-methylindane-2-carboxylic acid.
Organic Building Block
As a functionalised indene derivative, it functions as a versatile building block in multi-step organic syntheses, enabling the construction of novel molecular architectures.
| Molecular weight | 174.20 |
|---|---|
| Empirical formula | C11H10O2 |
| Assay | 98% |
| Application | 3-Methylindene-2-carboxylic acid was used in the synthesis of:• LKS01-B650, an imaging probe that selectively binds the catalytically active LMP7 subunit of immunoproteasome in living cells1• 1-methylindane-2-carboxylic acid via reduction with sodium amalgam2 |
| Melting point | 201-203 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylindene-2-carboxylic acid used for?
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3-Methylindene-2-carboxylic acid is primarily used as a building block in organic synthesis, including the preparation of imaging probes and other chemical entities for research purposes.
What are the CAS number and molecular formula of 3-Methylindene-2-carboxylic acid?
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The CAS number is 34225-81-5, and the molecular formula is C11H10O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methylindene-2-carboxylic acid with a minimum purity of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
What are the safety and handling recommendations for 3-Methylindene-2-carboxylic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. It has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is 3-Methylindene-2-carboxylic acid shipped and exported?
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3-Methylindene-2-carboxylic acid is carefully packed for secure transport and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample?
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To request a quote or a sample of 3-Methylindene-2-carboxylic acid, please contact our sales department via the website or by calling our customer service line.
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