(R)-(+)-1,2-Epoxybutane
(R)-(+)-1,2-Epoxybutane (CAS: 3760-95-0) is a chiral epoxide with the molecular formula C4H8O and a molecular weight of 72.11 g/mol. This optically active compound, exhibiting [α]20/D -10°, is a valuable building block in asymmetric synthesis. Its reactivity makes it suitable for incorporation into more complex organic molecules, serving as a key intermediate in the development of pharmaceuticals and fine chemicals.
- IUPAC
- (2R)-Ethyloxirane
- Synonyms
- (2R)-Ethyloxirane(R)-1,2-Epoxybutane

Chiral Building Block
Utilised as a fundamental chiral synthon in the stereoselective synthesis of complex organic molecules. Its epoxide ring can be opened regioselectively to introduce specific functionalities.
Asymmetric Synthesis
Serves as a crucial reagent in asymmetric synthesis, enabling the creation of enantiomerically enriched products. It is instrumental in the construction of chiral centres within target molecules.
Pharmaceutical Intermediates
Acts as an intermediate in the synthesis of various pharmaceutical agents. Its chiral nature is often critical for the biological activity of the final drug substance.
Organic Synthesis Reagent
A versatile reagent in general organic synthesis for creating difunctional compounds through epoxide ring-opening reactions. It can be used to introduce hydroxy and alkyl/aryl groups.
| Molecular weight | 72.11 |
|---|---|
| Empirical formula | C4H8O |
| Assay | 98% |
| Boiling point | 63 °C(lit.) |
| Density | 0.837 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.386(lit.) |
| Optical activity | [α]20/D −10°, neat |




Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -12 °C / 10.4 °F |
| Transport (UN / ADR) | UN 3022 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 20/21/22-34-40 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1,2-Epoxybutane used for?
+
(R)-(+)-1,2-Epoxybutane is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of pharmaceuticals and fine chemicals.
What are the CAS number and formula for (R)-(+)-1,2-Epoxybutane?
+
The CAS number is 3760-95-0 and the molecular formula is C4H8O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(+)-1,2-Epoxybutane with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should (R)-(+)-1,2-Epoxybutane be handled safely?
+
This substance is highly flammable and corrosive, posing significant health hazards including severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area. Refer to the safety data sheet for full details.
Is (R)-(+)-1,2-Epoxybutane a controlled substance?
+
The provided data does not indicate that (R)-(+)-1,2-Epoxybutane is a controlled substance.
How is (R)-(+)-1,2-Epoxybutane packed and shipped?
+
(R)-(+)-1,2-Epoxybutane is shipped under UN 3022, Hazard Class 3, Packing Group II, indicating it is a flammable liquid. TSS exports globally; please contact us for specific shipping and handling requirements.
How can I request a quote or sample for (R)-(+)-1,2-Epoxybutane?
+
To request a quote or sample, please visit the Tech Serve Solutions website or contact our sales team directly with your inquiry.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis