(R)-(+)-1,2-Bis(diphenylphosphino)propane
(R)-(+)-1,2-Bis(diphenylphosphino)propane (CAS: 67884-32-6) is a chiral diphosphine ligand with a molecular weight of 412.44 g/mol. Utilised primarily in asymmetric synthesis, it acts as a crucial component in chiral catalysts for enantioselective reactions. This compound is a key reagent for chemists seeking to control stereochemistry in organic transformations, particularly in the pharmaceutical and fine chemical industries. Its defined stereochemistry makes it valuable for producing enantiomerically pure compounds.
- IUPAC
- (R)-PROPHOS
- Synonyms
- (R)-(+)-1,2-Bis(diphenylphosphino)propane(R)-PROPHOS
Asymmetric Catalysis
Serves as a chiral ligand in transition metal catalysts for asymmetric hydrogenation, hydroformylation, and other enantioselective transformations. Its structure promotes high levels of stereocontrol in the synthesis of chiral molecules.
Organic Synthesis
A valuable reagent in complex organic synthesis, enabling the stereoselective construction of carbon-carbon and carbon-heteroatom bonds. It is instrumental in the synthesis of pharmaceutical intermediates and fine chemicals requiring specific stereoisomers.
Ligand for Metal Complexes
Forms stable complexes with various transition metals, creating active catalytic species. These complexes are employed in a wide range of homogeneous catalytic processes where chirality is essential.
| Molecular weight | 412.44 |
|---|---|
| Linear formula | (C6H5)2PCH(CH3)CH2P(C6H5)2 |
| Assay | 98% |
| Optical activity | [α]20/D +184°, c = 1 in acetone |
| Melting point | 71-73 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-1,2-Bis(diphenylphosphino)propane used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for enantioselective organic synthesis, particularly in the pharmaceutical and fine chemical sectors.
What is the CAS number and chemical formula for (R)-(+)-1,2-Bis(diphenylphosphino)propane?
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The CAS number is 67884-32-6. The linear formula is (C6H5)2PCH(CH3)CH2P(C6H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-1,2-Bis(diphenylphosphino)propane with an assay of 98%. This is a high-purity reagent suitable for research and synthesis. We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-1,2-Bis(diphenylphosphino)propane be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as an irritant (H315, H319, H335).
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, capable of handling and shipping (R)-(+)-1,2-Bis(diphenylphosphino)propane worldwide in compliance with international regulations.
How can I request a sample or quote?
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To request a sample or a quote for (R)-(+)-1,2-Bis(diphenylphosphino)propane, please contact our sales department via the website or by phone, providing your contact details and desired quantity.
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