Pyridostigmine bromide
Pyridostigmine bromide (CAS: 101-26-8), chemical formula C9H13BrN2O2, with a molecular weight of 261.12 g/mol, is a vital pharmaceutical intermediate and bioactive molecule. It functions as an acetylcholinesterase inhibitor. Its primary applications are in the treatment of myasthenia gravis and as an antidote for nerve agent exposure. This compound is critical in neurological research and therapeutic development due to its targeted mechanism of action.
- IUPAC
- 3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide
- Synonyms
- 3-(Dimethylcarbamoyloxy)-1-methylpyridinium bromideMestinonPyridostigmine(1+)Pyridostigminium bromide
Treatment of Myasthenia Gravis
Pyridostigmine bromide is a cornerstone therapy for myasthenia gravis, a chronic autoimmune disorder causing muscle weakness. It enhances neuromuscular transmission by inhibiting the breakdown of acetylcholine.
Antidote for Organophosphate Poisoning
It serves as a crucial agent in protecting against or treating exposure to certain nerve agents and organophosphate pesticides. By inhibiting acetylcholinesterase, it helps prevent the overstimulation of muscles and glands.
Neuroscience Research
As a selective acetylcholinesterase inhibitor, this compound is employed in research settings to study cholinergic pathways and neurotransmission in the central and peripheral nervous systems.
| Molecular weight | 261.12 |
|---|---|
| Empirical formula | C9H13BrN2O2 |
Hazard statements
- H300Fatal if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-43 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ACHE(43) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyridostigmine bromide used for?
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Pyridostigmine bromide is primarily used for the treatment of myasthenia gravis and as a prophylactic agent against nerve agent poisoning. It also finds application in neuroscience research as an acetylcholinesterase inhibitor.
What is the CAS number and formula for Pyridostigmine bromide?
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The CAS number for Pyridostigmine bromide is 101-26-8, and its chemical formula is C9H13BrN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pyridostigmine bromide typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated. Please refer to the product's Certificate of Analysis for specific purity details.
How should Pyridostigmine bromide be handled safely?
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Pyridostigmine bromide is a highly toxic substance (Danger, H300 +H310 + H330-H317). Handle with extreme caution, using appropriate personal protective equipment including eyeshields, gloves, and a full-face respirator with N100 cartridges. Avoid inhalation, skin contact, and ingestion.
How is Pyridostigmine bromide packed, shipped, and exported?
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Pyridostigmine bromide is carefully packed according to international transport regulations for hazardous materials (UN 2811, 6.1 / PGII). TSS exports globally, adhering to all relevant shipping and customs requirements.
How can I request a sample or quote for Pyridostigmine bromide?
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To request a sample or obtain a quote for Pyridostigmine bromide, please contact our sales department through the website or by phone, providing your contact details and intended quantity.
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